Description
Calculate an assay value relative to a nonzero supplied control.
Assay records separate concentration/effect units, control references, censoring and model parameters. An occupied/free complement assumes one common exhaustive total, while a control ratio is not automatically a percentage effect. Labels and local scalar operations do not fit a response model or establish potency, drug efficacy or an appropriate medication choice.
Calculate an assay value relative to a nonzero supplied control.
When to use this tool
Use PD Assay Control Relative Value when you already have assayValue, controlValue and need to calculate an assay value relative to a nonzero supplied control.
How to use the tool and how it works
- Enter assayValue, controlValue. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read relativeValue. Use the output convention below.
Require controlValue!=0; return assayValue/controlValue, retaining signed values.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| assayValue | Assay Value | Required. Finite number. |
| controlValue | Nonzero signed reference; no requirement that the ratio is a [0,1] response fraction. | Required. Finite number. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| relativeValue | Relative Value | Required. Finite number. |
{
"input": {
"assayValue": 6,
"controlValue": 4
},
"output": {
"relativeValue": 1.5
}
}Limitations and assumptions
- A relative value may be negative or exceed one; no assay normalization validity, potency, significance or clinical interpretation is established.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use the full assay controls, measurement units and response-model definition when estimating an effect. Fit or evaluate the intended concentration-response relationship explicitly; a control ratio, complement or parameter label does not infer that relationship.
References
Similar or alternative tools
- PD Reference Compound Tag
Tag an explicit assay reference-compound record.
- PD Occupancy To Free Fraction
Calculate free fraction as the complement of a supplied occupancy fraction.