Description
Explicit research grid point fractions and eligible sampled area. Excluded hits are excluded from the designated/viable denominator and reported as a fraction of all hits; this does not classify tissue.
Laboratory records distinguish specimen identity, sampling coverage, retained quantities, processing times, image scale, and measurement uncertainty. Areas, volumes, counts, and source-support flags measure different aspects of a record. A local calculation does not identify tissue or establish diagnostic adequacy.
Explicit research grid point fractions and eligible sampled area. Excluded hits are excluded from the designated/viable denominator and reported as a fraction of all hits; this does not classify tissue.
When to use this tool
Use Necrotic Area Research Grid Share when you need this specimen-record, sampling, processing-time, dimensional, or uncertainty calculation.
How to use the tool and how it works
- Enter designatedHits, viableHits, excludedHits, pointsPerArea. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read eligiblePoints, designatedFraction, sampledArea, excludedFraction. Use the output convention below.
For nonnegative integer designatedHits, viableHits, and excludedHits require designated+viable>0 and positive pointsPerArea. Return eligiblePoints=designated+viable, designatedFraction=designated/eligible, excludedFraction=excluded/(eligible+excluded), and sampledArea=eligible/pointsPerArea.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| designatedHits | Designated Hits | Required. Safe integer; minimum 0. |
| viableHits | Viable Hits | Required. Safe integer; minimum 0. |
| excludedHits | Excluded Hits | Required. Safe integer; minimum 0. |
| pointsPerArea | Positive eligible sampling points per area unit. | Required. Finite number; strictly above 0. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| eligiblePoints | Eligible Points | Required. Safe integer. |
| designatedFraction | Designated Fraction | Required. Finite number. |
| sampledArea | Sampled Area | Required. Finite number. |
| excludedFraction | Excluded Fraction | Required. Finite number. |
{
"input": {
"designatedHits": 20,
"viableHits": 80,
"excludedHits": 10,
"pointsPerArea": 50
},
"output": {
"excludedFraction": 0.09090909090909091,
"eligiblePoints": 100,
"designatedFraction": 0.2,
"sampledArea": 2
}
}Limitations and assumptions
- PointsPerArea is eligible sampling points per area unit. Categories and grid density are supplied; the arithmetic does not classify necrosis, validate stereological sampling, or establish clinical tumor features.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Signed zero is exported as zero.
Alternative or Complementary methods
Use validated laboratory procedures, traceable measurements, and authenticated specimen records for a complete assessment. Check the relevant sampling and processing assumptions before interpreting a local quantity.
References
Similar or alternative tools
- Tumor Research Cellularity Count Fraction
Descriptive fraction from caller-classified research counts; no cell identification, pathology grade or treatment implication.
- Tissue Block Sampling Share
Sum all volumes into totalVolume and selected valid-source volumes into sampledValidVolume; return their share when positive, otherwise zero with defined=false.