Process Efficiency

Measure total analytical process efficiency relative to a neat standard.

Description

Process efficiency relates a pre-extraction spiked signal to a neat standard.

Process efficiency relates a pre-extraction spiked signal to a neat standard. The comparison combines extraction and matrix effects rather than separating them.^[1]

Measure total analytical process efficiency relative to a neat standard.

When to use Process Efficiency

Use this tool to measure total analytical process efficiency relative to a neat standard.

Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.

How to use Process Efficiency and understand its results

Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
Enter preExtractionSpikeArea, neatStandardArea using the field table and calculation rules, then run the tool.
Read processEfficiencyPercent. The explanation below defines the units, signs, ordering and any flags or placeholder values.
If the tool reports an input issue, correct the values and run it again. Apply the stated assumptions when interpreting a successfully returned result.

Input field	Meaning	Value type; see rules below	Requirement
preExtractionSpikeArea	Pre extraction spike area	number	Required
neatStandardArea	Neat standard area	number	Required

Enter nonnegative pre-extraction area and positive neat-standard area. Return percentage, which may exceed 100.

efficiency%=100 preExtractionSpikeArea/neatStandardArea

Units, indexing, boundary conditions and exceptional cases are defined in the calculation rules above.

Output field	Meaning	Value type
processEfficiencyPercent	Process efficiency percent	number

json

{
  "input": {
    "preExtractionSpikeArea": 80,
    "neatStandardArea": 100
  },
  "output": {
    "processEfficiencyPercent": 80
  }
}

Limitations and assumptions

Concentrations, injection amounts and instrument conditions must be comparable. No separate recovery or ion-suppression estimate is derived.

Numeric inputs must be finite. Follow the calculation-specific rules for overflow, underflow and exceptional cases. Missing required fields, extra fields, wrong value types and violations of the calculation rules are input errors.

Alternative or Complementary methods

Use Matrix Ion Suppression: Quantify matrix-induced ion suppression or enhancement using a post-extraction spike. For a complementary task, use Internal Standard Normalization: Normalize analyte peak areas against matched internal-standard injections.

References

Process Efficiency — tool.io

Similar or alternative tools

Matrix Ion Suppression
Quantify matrix-induced ion suppression or enhancement using a post-extraction spike.
Internal Standard Normalization
Normalize analyte peak areas against matched internal-standard injections.