DDA Cycle Budget

Calculate top-N DDA scan-cycle time and remaining budget.

Description

DDA cycle budgeting combines one MS1 scan with a selected number of MS2 scans.

DDA cycle budgeting combines one MS1 scan with a selected number of MS2 scans. Remaining time compares that sum with a cycle budget.^[1]

Calculate top-N DDA scan-cycle time and remaining budget.

When to use DDA Cycle Budget

Use this tool to calculate top-N DDA scan-cycle time and remaining budget.

Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.

How to use DDA Cycle Budget and understand its results

Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
Enter ms1TimeMs, ms2TimeMs, topN, maximumCycleMs using the field table and calculation rules, then run the tool.
Read cycleTimeMs, remainingBudgetMs, withinBudget. The explanation below defines the units, signs, ordering and any flags or placeholder values.
If the tool reports an input issue, correct the values and run it again. Apply the stated assumptions when interpreting a successfully returned result.

Input field	Meaning	Value type; see rules below	Requirement
ms1TimeMs	Ms 1 time ms	number	Required
ms2TimeMs	Ms 2 time ms	number	Required
topN	Top n	number	Required
maximumCycleMs	Maximum cycle ms	number	Required

Enter nonnegative scan durations, nonnegative safe integer topN and positive budget on the same time basis. Return cycle, remaining time and inclusive cycle≤budget flag.

cycle=MS1duration+topN×MS2duration; remaining=budget−cycle

Units, indexing, boundary conditions and exceptional cases are defined in the calculation rules above.

Output field	Meaning	Value type
cycleTimeMs	Cycle time ms	number
remainingBudgetMs	Remaining budget ms	number
withinBudget	Within budget	boolean

json

{
  "input": {
    "ms1TimeMs": 100,
    "ms2TimeMs": 50,
    "topN": 4,
    "maximumCycleMs": 350
  },
  "output": {
    "cycleTimeMs": 300,
    "remainingBudgetMs": 50,
    "withinBudget": true
  }
}

Limitations and assumptions

No precursor selection or variable scan timing is modeled. Include overhead in the supplied durations or budget.

Numeric inputs must be finite. Follow the calculation-specific rules for overflow, underflow and exceptional cases. Missing required fields, extra fields, wrong value types and violations of the calculation rules are input errors. A successfully returned false flag is an evaluated outcome; its meaning is explained above.

Alternative or Complementary methods

Use Polarity Duty Cycle: Break down positive/negative ionization duty cycle and switching overhead. For a complementary task, use DIA Window Planner: Partition a DIA m/z span into contiguous isolation windows.

References

DDA Cycle Budget — tool.io

Similar or alternative tools

Polarity Duty Cycle
Break down positive/negative ionization duty cycle and switching overhead.
DIA Window Planner
Partition a DIA m/z span into contiguous isolation windows.