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Cardiac Research Fractional Area Change Tool

Descriptive model area change with independent endpoint bounds, without a function assessment or clinical threshold.

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Description

Return fractional area change and supplied-uncertainty bounds.

Cardiac measurement formulas depend on geometry, units, calibration and reference origins. A Doppler projection correction, echo disc-volume contribution or waveform integral evaluates supplied quantities without validating image acquisition, signal quality or physiological interpretation.

Return fractional area change and supplied-uncertainty bounds.

When to use this tool

Use Cardiac Research Fractional Area Change when checking one supplied cardiac measurement, geometry or calibration term.

How to use the tool and how it works

  1. Enter maximumArea, minimumArea, maximumUncertainty, minimumUncertainty. Use the units and conventions below.
  2. Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
  3. Read fractionalAreaChange, conservativeLower, conservativeUpper. Use the output convention below.

Return fractional area change and supplied-uncertainty bounds. Require maxArea > 0, minArea within max, maxUncertainty < max and nonnegative uncertainties; nominal = 1-min/max, lower = 1-(min+uMin)/(max-uMax), upper = 1-max(0,min-uMin)/(max+uMax).1

Input fieldMeaning and unitsAccepted input
maximumAreaMaximum AreaRequired. Finite number; strictly above 0.
minimumAreaMinimum AreaRequired. Finite number; minimum 0.
maximumUncertaintyMaximum UncertaintyRequired. Finite number; minimum 0.
minimumUncertaintyMinimum UncertaintyRequired. Finite number; minimum 0.
Output fieldInterpretationReturned shape
fractionalAreaChangeFractional Area ChangeRequired. Finite number.
conservativeLowerLower fractional-area-change envelope; can be negative under the supplied area bounds.Required. Finite number.
conservativeUpperConservative UpperRequired. Finite number.
json
{
  "input": {
    "maximumArea": 20,
    "minimumArea": 10,
    "maximumUncertainty": 1,
    "minimumUncertainty": 1
  },
  "output": {
    "fractionalAreaChange": 0.5,
    "conservativeLower": 0.42105263157894735,
    "conservativeUpper": 0.5714285714285714
  }
}

Limitations and assumptions

  • The lower bound can be negative; these are deterministic supplied area envelopes, not confidence intervals or clinical thresholds.
  • Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
  • Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.

Alternative or Complementary methods

Use validated acquisition and calibration, a complete appropriate measurement method and qualified clinical interpretation; assess measurement uncertainty and model assumptions separately.

References

  1. Calculation and input contract: cardiology/cardiac-research-fractional-area-change — tool.io

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