Description
Return ideal small-solute retention under diafiltration.
Laboratory quantities depend on sample volume, concentration basis, blank correction, geometry and calibration. A dilution, recovery fraction or signal correction evaluates a supplied measurement model without validating the assay, identifying a substance or establishing biological or clinical performance.
Return ideal small-solute retention under diafiltration.
When to use this tool
Use Diafiltration Ideal Small Solute Retention when checking the stated laboratory bookkeeping, signal, sample or measurement convention.
How to use the tool and how it works
- Enter diavolumes, sievingCoefficient. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read remainingFraction. Use the output convention below.
Return ideal small-solute retention under diafiltration. Require diavolumes >= 0 and sievingCoefficient in [0,1]; remainingFraction = exp(-sieving*diavolumes).1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| diavolumes | Diavolumes | Required. Finite number; minimum 0. |
| sievingCoefficient | Supplied fraction 0..1 for an ideal well-mixed constant-volume model. | Required. Finite number; minimum 0; maximum 1. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| remainingFraction | Remaining Fraction | Required. Finite number. |
{
"input": {
"diavolumes": 2,
"sievingCoefficient": 1
},
"output": {
"remainingFraction": 0.1353352832366127
}
}Limitations and assumptions
- This assumes constant-volume ideal mixing and constant sieving; no adsorption, changing retention or actual separation performance is modeled.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use verified sample records, calibrated equipment and an appropriate validated measurement method; assess uncertainty and practical laboratory conditions independently.
References
Similar or alternative tools
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