Description
Return an ohmic ion-channel current and residual.
Membrane electrical quantities distinguish total from area-specific properties, concentration ratios from activities and single-ion from multi-ion models. Local capacitance, current or potential terms require compatible sign, valence, temperature and unit conventions without themselves validating a biological membrane.
Return an ohmic ion-channel current and residual.
When to use this tool
Use Ion Channel Conductance Current Gap when evaluating the stated membrane, ionic or area-basis term.
How to use the tool and how it works
- Enter conductance, membraneVolts, reversalVolts, measuredCurrent. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read drivingVoltage, predictedCurrent, residual. Use the output convention below.
Return an ohmic ion-channel current and residual. Require conductance >= 0; drivingVoltage = membraneVolts-reversalVolts, predictedCurrent = conductance*drivingVoltage, residual = measuredCurrent-predictedCurrent.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| conductance | Conductance | Required. Finite number; minimum 0. |
| membraneVolts | Membrane Volts | Required. Finite number. |
| reversalVolts | Reversal Volts | Required. Finite number. |
| measuredCurrent | Measured Current | Required. Finite number. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| drivingVoltage | Driving Voltage | Required. Finite number. |
| predictedCurrent | Predicted Current | Required. Finite number. |
| residual | Signed difference in the direction stated above, with matching units. | Required. Finite number. |
{
"input": {
"conductance": 2,
"membraneVolts": 0.03,
"reversalVolts": -0.02,
"measuredCurrent": 0.12
},
"output": {
"drivingVoltage": 0.05,
"predictedCurrent": 0.1,
"residual": 0.01999999999999999
}
}Limitations and assumptions
- Conductance in siemens and volts give amperes; voltage-dependent gating, concentrations and the reversal potential are not inferred.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use verified concentrations, activities, geometry and electrical calibration with the appropriate complete membrane/channel model for physiological interpretation.
References
Similar or alternative tools
- Ion Valence Potential Sign
Return electrostatic energy change and sign.
- Goldman One Ion Permeability Contribution
Return one Goldman concentration-weight contribution.