Description
Return one Goldman concentration-weight contribution.
Membrane electrical quantities distinguish total from area-specific properties, concentration ratios from activities and single-ion from multi-ion models. Local capacitance, current or potential terms require compatible sign, valence, temperature and unit conventions without themselves validating a biological membrane.
Return one Goldman concentration-weight contribution.
When to use this tool
Use Goldman One Ion Permeability Contribution when evaluating the stated membrane, ionic or area-basis term.
How to use the tool and how it works
- Enter permeability, outside, inside, anion. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read numeratorContribution, denominatorContribution. Use the output convention below.
Return one Goldman concentration-weight contribution. Require nonnegative permeability/outside/inside; cations use permeability*outside in the numerator and permeability*inside in the denominator, while anions reverse those concentrations.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| permeability | Permeability | Required. Finite number; minimum 0. |
| outside | Outside | Required. Finite number; minimum 0. |
| inside | Inside | Required. Finite number; minimum 0. |
| anion | Reverses the numerator/denominator concentration placement under this monovalent contribution convention. | Required. Boolean. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| numeratorContribution | Numerator Contribution | Required. Finite number. |
| denominatorContribution | Denominator Contribution | Required. Finite number. |
{
"input": {
"permeability": 2,
"outside": 10,
"inside": 1,
"anion": false
},
"output": {
"numeratorContribution": 20,
"denominatorContribution": 2
}
}Limitations and assumptions
- This is one concentration term under the usual monovalent convention, not a complete Goldman voltage, current or equilibrium calculation.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use verified concentrations, activities, geometry and electrical calibration with the appropriate complete membrane/channel model for physiological interpretation.
References
Similar or alternative tools
- Ion Channel Conductance Current Gap
Return an ohmic ion-channel current and residual.
- Ion Valence Potential Sign
Return electrostatic energy change and sign.