Use X-Linked Male Frequency when you need to compute the frequency of affected males for an X-linked recessive trait, equal to the recessive allele frequency q under Hardy-Weinberg assumptions. Enter Recessive allele frequency using the definitions and units below so the result can be reproduced.

Recessive allele frequency

A finite measured or assumed value from 0 through 1.

The published tool contract uses this rule: Compute the frequency of affected males for an X-linked recessive trait, equal to the recessive allele frequency q under Hardy-Weinberg assumptions.

Affected male frequency

The calculated affected male frequency.

The calculation does not propagate measurement uncertainty, sampling error, or biological and chemical variability. Recessive allele frequency must remain between 0 and 1.

Retain the original Recessive allele frequency values and their units alongside the result. Genotype Frequencies is useful when you instead need to compute expected Hardy-Weinberg genotype frequencies p^2, 2pq, and q^2 from an allele frequency. Allele Frequency p provides another view by helping you estimate dominant allele frequency p from genotype counts using p = (2*AA + Aa) / (2*total).

• Genotype Frequencies

  Compute expected Hardy-Weinberg genotype frequencies p^2, 2pq, and q^2 from an allele frequency.

• Allele Frequency p

  Estimate dominant allele frequency p from genotype counts using p = (2*AA + Aa) / (2*total).

• Carrier Frequency

  Estimate heterozygous carrier frequency 2q(1-q) from the incidence q^2 of a recessive disease.