Genotype Frequencies
Compute expected Hardy-Weinberg genotype frequencies p^2, 2pq, and q^2 from an allele frequency.
Description
Compute expected Hardy-Weinberg genotype frequencies p^2, 2pq, and q^2 from an allele frequency.
Genotype Frequencies is a focused biology tool that compute expected Hardy-Weinberg genotype frequencies p^2, 2pq, and q^2 from an allele frequency. It calculates locally from the values you enter and exposes the result without changing the source observations.1
When to use Genotype Frequencies
Use Genotype Frequencies when you need to compute expected Hardy-Weinberg genotype frequencies p^2, 2pq, and q^2 from an allele frequency. Enter Allele frequency p using the definitions and units below so the result can be reproduced.
- Allele frequency p
- A finite measured or assumed value from 0 through 1.
How Genotype Frequencies calculates the result
The published tool contract uses this rule: Compute expected Hardy-Weinberg genotype frequencies p^2, 2pq, and q^2 from an allele frequency.
- Expected AA
- The calculated expected aa.
- Expected Aa
- The calculated expected aa.
- Expected aa
- The calculated expected aa.
Limitations of Genotype Frequencies
The calculation does not propagate measurement uncertainty, sampling error, or biological and chemical variability. Allele frequency p must remain between 0 and 1.
Alternative or Complementary measurements
Retain the original Allele frequency p values and their units alongside the result. X-Linked Male Frequency is useful when you instead need to compute the frequency of affected males for an X-linked recessive trait, equal to the recessive allele frequency q under Hardy-Weinberg assumptions. Allele Frequency p provides another view by helping you estimate dominant allele frequency p from genotype counts using p = (2*AA + Aa) / (2*total).
References
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Hardy–Weinberg principle — Wikipedia contributors
Similar or alternative tools
- X-Linked Male Frequency
Compute the frequency of affected males for an X-linked recessive trait, equal to the recessive allele frequency q under Hardy-Weinberg assumptions.
- Allele Frequency p
Estimate dominant allele frequency p from genotype counts using p = (2*AA + Aa) / (2*total).
- Carrier Frequency
Estimate heterozygous carrier frequency 2q(1-q) from the incidence q^2 of a recessive disease.