LTD Magnitude Calculator
Actual LTDpercentageDECREASEpositivewhen post<baseline, negative enhancement retained. Qualified protocol independent, no automatically classify LTD. Actual independently matched observations/units and protocol, not diagnosis, causal mechanism, clinical decision or validated individual prediction.
Description
An LTD magnitude convention expresses response reduction as a positive percentage of baseline.
An LTD magnitude convention expresses response reduction as a positive percentage of baseline.1
This tool retains a negative result for an increase rather than automatically labeling a response as depression.
When to use LTD Magnitude Calculator
This tool retains a negative result for an increase rather than automatically labeling a response as depression.
How to use LTD Magnitude Calculator and how it works
- Prepare qualified post ltd response, qualified baseline response, using the input definitions and matching units below.
- Enter the required fields and run LTD Magnitude Calculator.
- Read result.value using the units, signs and ordering explained below.
- Correct any rejected inputs and rerun; interpret the result within the stated model and its assumptions.
| Input field | Meaning | Value type | Requirement |
|---|---|---|---|
| actualQualifiedPostLtdResponse | Actual Qualified Post Ltd Response. Use the units and matching context stated in the calculation below. | number | Required; nonnegative; finite; other constraints below |
| actualQualifiedBaselineResponse | Actual Qualified Baseline Response. Use the units and matching context stated in the calculation below. | number | Required; strictly positive; finite; other constraints below |
Require nonnegative matched post-LTD response and positive baseline. Return 100*(1-post/baseline). A smaller post response gives a positive decrease, while enhancement gives a negative result. No biological LTD classification is assigned.
decreasePercent=100*(1-post/baseline) Apply the input ordering, units and branch conditions stated above.
| Output field | Meaning | Value type |
|---|---|---|
| result | Object containing the calculated or selected fields below. | object |
| result.value | Percentage under the stated numerator, denominator and sign convention. | number |
{
"input": {
"actualQualifiedPostLtdResponse": 1,
"actualQualifiedBaselineResponse": 2
},
"output": {
"result": {
"value": 50
}
}
}Limitations and assumptions
The calculation uses the supplied observations and model inputs. It does not collect measurements, select a reference population or coefficient, or establish that the model applies to the actual case. The stated branch conditions and output units remain part of the result.
All fields require explicit values. Unexpected fields, wrong types, nonfinite numbers and sparse arrays are rejected. Alignment, bounds and supported-token rules are explained above; extremely large inputs or nonfinite results can also fail. Input errors differ from successful false comparisons, unavailable-domain flags and empty match lists.
Alternative or Complementary methods
Use Mini Amplitude Calculator for a complementary operation: A miniature synaptic event amplitude can retain its polarity as peak minus baseline.
Use LTP Magnitude Calculator for a complementary operation: An LTP magnitude convention can express post-response increase relative to a matched baseline.
References
-
LTD Magnitude Calculator — tool.io
Similar or alternative tools
- Mini Amplitude Calculator
A miniature synaptic event amplitude can retain its polarity as peak minus baseline.
- LTP Magnitude Calculator
An LTP magnitude convention can express post-response increase relative to a matched baseline.