Polyamine Progression
Summarize a caller-measured putrescine-to-spermine abundance profile.
Description
Polyamine progression here summarizes the relative amount of spermine in a three-component pool.
Polyamine progression here summarizes the relative amount of spermine in a three-component pool. Composition does not measure conversion kinetics.1
Summarize a caller-measured putrescine-to-spermine abundance profile.
When to use Polyamine Progression
Use this tool to summarize a caller-measured putrescine-to-spermine abundance profile.
Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
How to use Polyamine Progression and understand its results
- Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
- Enter putrescine, spermidine, spermine using the field table and calculation rules, then run the tool.
- Read totalPolyamines, spermineSharePercent, dominantStage. The explanation below defines the units, signs, ordering and any flags or placeholder values.
- If the tool reports an input issue, correct the values and run it again. Apply the stated assumptions when interpreting a successfully returned result.
| Input field | Meaning | Value type; see rules below | Requirement |
|---|---|---|---|
| putrescine | Putrescine | number | Required |
| spermidine | Spermidine | number | Required |
| spermine | Spermine | number | Required |
Enter nonnegative compatible amounts with positive total. Return total, spermine percentage and largest component; ties prefer spermine, then spermidine, then putrescine.
total=putrescine+spermidine+spermine; spermine%=100 spermine/total Units, indexing, boundary conditions and exceptional cases are defined in the calculation rules above.
| Output field | Meaning | Value type |
|---|---|---|
| totalPolyamines | Total polyamines | number |
| spermineSharePercent | Spermine share percent | number |
| dominantStage | Dominant stage | string |
{
"input": {
"putrescine": 2,
"spermidine": 4,
"spermine": 6
},
"output": {
"totalPolyamines": 12,
"spermineSharePercent": 50,
"dominantStage": "spermine"
}
}Limitations and assumptions
Other polyamines and compartments are excluded. No pathway rate or biological stage is determined.
Numeric inputs must be finite. Follow the calculation-specific rules for overflow, underflow and exceptional cases. Missing required fields, extra fields, wrong value types and violations of the calculation rules are input errors.
Alternative or Complementary methods
Use SCFA Composition: Calculate acetate–propionate–butyrate molar percentages. For a complementary task, use Sterol Conversion Progress: Summarize lanosterol and cholesterol fractions as a conversion proxy, not flux.
References
-
Polyamine Progression — tool.io
Similar or alternative tools
- SCFA Composition
Calculate acetate–propionate–butyrate molar percentages.
- Sterol Conversion Progress
Summarize lanosterol and cholesterol fractions as a conversion proxy, not flux.