Creatinine Normalized Excretion
Normalize urinary metabolite concentration to creatinine.
Description
Creatinine normalization expresses an analyte concentration relative to urine creatinine.
Creatinine normalization expresses an analyte concentration relative to urine creatinine. With µmol/L divided by mmol/L, the quotient has units µmol/mmol.1
Normalize urinary metabolite concentration to creatinine.
When to use Creatinine Normalized Excretion
Use this tool to normalize urinary metabolite concentration to creatinine.
Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
How to use Creatinine Normalized Excretion and understand its results
- Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
- Enter urinaryAnalyteUmolL, urinaryCreatinineMmolL using the field table and calculation rules, then run the tool.
- Read umolPerMmolCreatinine. The explanation below defines the units, signs, ordering and any flags or placeholder values.
- If the tool reports an input issue, correct the values and run it again. Apply the stated assumptions when interpreting a successfully returned result.
| Input field | Meaning | Value type; see rules below | Requirement |
|---|---|---|---|
| urinaryAnalyteUmolL | Urinary analyte umol l | number | Required |
| urinaryCreatinineMmolL | Urinary creatinine mmol l | number | Required |
Enter nonnegative analyte and positive creatinine concentration. Return normalized ratio.
normalized=analyteUmolL/creatinineMmolL Units, indexing, boundary conditions and exceptional cases are defined in the calculation rules above.
| Output field | Meaning | Value type |
|---|---|---|
| umolPerMmolCreatinine | Umol per mmol creatinine | number |
{
"input": {
"urinaryAnalyteUmolL": 20,
"urinaryCreatinineMmolL": 2
},
"output": {
"umolPerMmolCreatinine": 10
}
}Limitations and assumptions
No urine volume or collection duration is used, so this is not an excretion rate. Clinical interpretation and dilution suitability require separate review.
Numeric inputs must be finite. Follow the calculation-specific rules for overflow, underflow and exceptional cases. Missing required fields, extra fields, wrong value types and violations of the calculation rules are input errors.
Alternative or Complementary methods
Use Urine Specific Gravity Correction: Correct urine concentration to a caller-selected specific-gravity reference. For a complementary task, use Freezing Point Osmolality: Estimate osmolality by a caller-calibrated freezing-point depression.
References
-
Creatinine Normalized Excretion — tool.io
Similar or alternative tools
- Urine Specific Gravity Correction
Correct urine concentration to a caller-selected specific-gravity reference.
- Freezing Point Osmolality
Estimate osmolality by a caller-calibrated freezing-point depression.