Bile Acid Hydrophobicity

Compute a weighted bile-acid hydrophobicity index from caller weights.

Description

A bile-acid hydrophobicity index is an amount-weighted average of supplied component weights.

A bile-acid hydrophobicity index is an amount-weighted average of supplied component weights. The caller determines both composition and weight convention.^[1]

Compute a weighted bile-acid hydrophobicity index from caller weights.

When to use Bile Acid Hydrophobicity

Use this tool to compute a weighted bile-acid hydrophobicity index from caller weights.

Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.

How to use Bile Acid Hydrophobicity and understand its results

Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
Enter bileAcidAmounts, hydrophobicityWeights using the field table and calculation rules, then run the tool.
Read weightedHydrophobicity, totalAmount. The explanation below defines the units, signs, ordering and any flags or placeholder values.
If the tool reports an input issue, correct the values and run it again. Apply the stated assumptions when interpreting a successfully returned result.

Input field	Meaning	Value type; see rules below	Requirement
bileAcidAmounts	Bile acid amounts	list of number	Required
hydrophobicityWeights	Hydrophobicity weights	list of number	Required

Enter nonempty aligned nonnegative amounts and finite signed weights with positive total amount. Return weighted index and total.

index=Σamount_i×weight_i/Σamount_i

Units, indexing, boundary conditions and exceptional cases are defined in the calculation rules above.

Output field	Meaning	Value type
weightedHydrophobicity	Weighted hydrophobicity	number
totalAmount	Total amount	number

json

{
  "input": {
    "bileAcidAmounts": [
      1,
      3
    ],
    "hydrophobicityWeights": [
      -1,
      1
    ]
  },
  "output": {
    "weightedHydrophobicity": 0.5,
    "totalAmount": 4
  }
}

Limitations and assumptions

No weight catalog, structural classification or physiological outcome is supplied.

Numeric inputs must be finite. Follow the calculation-specific rules for overflow, underflow and exceptional cases. Lists are limited to 100,000 entries; the rules above may require smaller limits. Missing required fields, extra fields, wrong value types and violations of the calculation rules are input errors.

Alternative or Complementary methods

Use Sterol Conversion Progress: Summarize lanosterol and cholesterol fractions as a conversion proxy, not flux. For a complementary task, use SCFA Composition: Calculate acetate–propionate–butyrate molar percentages.

References

Bile Acid Hydrophobicity — tool.io

Similar or alternative tools

Sterol Conversion Progress
Summarize lanosterol and cholesterol fractions as a conversion proxy, not flux.
SCFA Composition
Calculate acetate–propionate–butyrate molar percentages.