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Tablet Friability Bench Mass Loss Term Tool

Calculate tablet friability bench mass loss term from explicit caller-supplied inputs.

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Description

Subtract excluded masses separately from initialMass and finalMass, require positive eligibleInitial, and return 1 - eligibleFinal/eligibleInitial as lossFraction.

Manufacturing mass comparisons depend on tare, moisture, exclusions, and dry-solids bases. A yield or residual is a bench accounting result rather than a quality-release decision.

Subtract excluded masses separately from initialMass and finalMass, require positive eligibleInitial, and return 1 - eligibleFinal/eligibleInitial as lossFraction.

When to use this tool

Use Tablet Friability Bench Mass Loss Term when you need one explicit pharmaceutical mass-basis calculation.

How to use the tool and how it works

  1. Enter initialMass, finalMass, excludedInitialMass, excludedFinalMass. Use the units and conventions below.
  2. Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
  3. Read eligibleInitial, eligibleFinal, lossFraction. Use the output convention below.

Subtract excluded masses separately from initialMass and finalMass, require positive eligibleInitial, and return 1 - eligibleFinal/eligibleInitial as lossFraction.1

Input fieldMeaning and unitsAccepted input
initialMassInitial MassRequired. Finite number.
finalMassFinal MassRequired. Finite number.
excludedInitialMassExcluded Initial MassRequired. Finite number; minimum 0.
excludedFinalMassExcluded Final MassRequired. Finite number; minimum 0.
Output fieldInterpretationReturned shape
eligibleInitialEligible InitialRequired. Finite number.
eligibleFinalEligible FinalRequired. Finite number.
lossFractionLoss FractionRequired. Finite number.
json
{
  "input": {
    "initialMass": 100,
    "finalMass": 98,
    "excludedInitialMass": 10,
    "excludedFinalMass": 9
  },
  "output": {
    "eligibleInitial": 90,
    "eligibleFinal": 89,
    "lossFraction": 0.011111111111111072
  }
}

Limitations and assumptions

  • Final mass may exceed initial eligible mass, yielding negative loss; no friability acceptance limit or compendial test procedure is selected.
  • Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
  • Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.

Alternative or Complementary methods

Use the validated procedure, original batch records, and approved quality criteria for manufacturing decisions.

References

  1. Calculation and input contract: industrial-pharmacy/tablet-friability-bench-mass-loss-term — tool.io

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