Paternity Combined Paternity Index CPI Multiplication Aggregator

Multiply supplied locus paternity likelihood ratios through log space under explicit independence; no prior probability or identity conclusion.

Description

Multiply supplied locus paternity likelihood ratios through log space under explicit independence; no prior probability or identity conclusion.

A combined paternity index multiplies locus likelihood ratios under a conditional-independence model. Reporting its logarithm helps expose the scale of the combined evidence.

When to use this tool

Multiply supplied locus paternity likelihood ratios through log space under explicit independence; no prior probability or identity conclusion.

  • Prepare the supplied locusLikelihoodRatios fields for this operation.
  • Compare the complete example with the representation used by your own input before carrying the result into another step.

How to use the tool and how it works

  1. Enter locusLikelihoodRatios. Use the exact text syntax, units and index conventions explained below.
  2. Run the tool. If input validation fails, correct the supplied fields before interpreting any result.
  3. Read result.log10Cpi, result.cpi, result.assumption, result.paternityEstablished. Interpret false, null and empty lists using the distinctions below; they can be valid outputs.

Require a nonempty positive locusLikelihoodRatios list. Sum their base-ten logarithms, return that sum as log10Cpi and 10 raised to it as cpi, with the conditional-locus-independence assumption and paternityEstablished false.1

Input fieldMeaning and representationAccepted input
locusLikelihoodRatioslocus likelihood ratios.List of finite numbers; bounded by the operation
Output fieldInterpretation
resultObject containing the named outputs below.
result.log10CpiThe log10 cpi value under the stated formula or text convention.
result.cpiThe cpi value under the stated formula or text convention.
result.assumptionThe assumption value under the stated formula or text convention.
result.paternityEstablishedAlways false: supplied likelihood arithmetic is not a parentage determination.
json
{
  "input": {
    "locusLikelihoodRatios": [
      2,
      5
    ]
  },
  "output": {
    "result": {
      "log10Cpi": 1,
      "cpi": 10,
      "assumption": "conditional-locus-independence",
      "paternityEstablished": false
    }
  }
}

Limitations and assumptions

  • No prior probability, mutation model, linkage correction or laboratory validation is supplied. Extremely large products producing nonfinite output are rejected; the result is not a legal parentage determination.
  • Every declared top-level field is required and unexpected fields are rejected. Numeric inputs must be finite; ordinary text fields are bounded to 8,192 UTF-16 code units, with tighter operation-specific limits where stated.
  • Ordinary string lists have at most 128 entries of at most 128 code units each; numeric lists and matrices have separate bounded size checks. Nonfinite results and excessively large serialized outputs are rejected.
  • Indexes are zero-based and spans have an exclusive end unless explicitly stated otherwise. A valid false, null or empty-list result is distinct from malformed input.

Alternative or Complementary methods

Keep model assumptions and phenotype-category order with each result. Ratio tolerance screens differ from goodness-of-fit inference, and sequence matches or likelihood products do not independently establish a biological mechanism or personal identity.

References

  1. Tool behavior and example: Paternity Combined Paternity Index CPI Multiplication Aggregator — tool.io

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