Description
Return 2p(1-p)(1-F) heterozygosity and both homozygote frequencies with added Fp(1-p).
Population-genetic fitness models use explicit allele frequencies, genotype fitnesses and generation rules. Relative fitness and a selection coefficient require a sign convention, and a deterministic update describes a model rather than an observed population trajectory.
Return 2p(1-p)(1-F) heterozygosity and both homozygote frequencies with added Fp(1-p).
When to use this tool
Use Inbreeding Heterozygote Deficit Term when you need a supplied one-step fitness or allele-frequency relationship.
How to use the tool and how it works
- Enter p, inbreeding. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read heterozygosity, homozygousFirst, homozygousSecond. Use the output convention below.
Require focal frequency and inbreeding in [0, 1]. Return 2p(1-p)(1-F) heterozygosity and both homozygote frequencies with added Fp(1-p).1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| p | P | Required. Finite number; minimum 0; maximum 1. |
| inbreeding | Inbreeding | Required. Finite number; minimum 0; maximum 1. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| heterozygosity | Heterozygosity | Required. Finite number. |
| homozygousFirst | Homozygous First | Required. Finite number. |
| homozygousSecond | Homozygous Second | Required. Finite number. |
{
"input": {
"p": 0.5,
"inbreeding": 0.2
},
"output": {
"heterozygosity": 0.4,
"homozygousFirst": 0.3,
"homozygousSecond": 0.3
}
}Limitations and assumptions
- F is a supplied heterozygote-deficit parameter and excludes negative values under this contract. No individual pedigree, population estimate or health inference is established.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use a population model appropriate to mating, selection, mutation, migration and drift. Estimate parameters and uncertainty from suitable data instead of treating a supplied model step as a prediction.
References
Similar or alternative tools
- Selection One Generation Allele Update
Return that mean and [p²wAA+p(1-p)wAa]/mean as nextP.
- Allele Count Frequency Residual
Return allele/called frequency and observed-minus-supplied residual.