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Lineage Division Interval Gap Tool

Calculate lineage division interval gap from explicit caller-supplied inputs.

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Description

Return lineage division interval and reference gap.

Developmental stages and lineages can be represented by labels, ordered events and observation intervals. Index and time differences preserve a declared representation but do not discover lineage, assign stage or establish biological equivalence.

Return lineage division interval and reference gap.

When to use this tool

Use Lineage Division Interval Gap when checking an explicit stage, lineage or observation-coordinate convention.

How to use the tool and how it works

  1. Enter parentDivisionAt, childDivisionAt, suppliedReferenceInterval. Use the units and conventions below.
  2. Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
  3. Read generationInterval, intervalGap. Use the output convention below.

Return lineage division interval and reference gap. Require childDivisionAt >= parentDivisionAt and nonnegative suppliedReferenceInterval; subtract parent from child, then subtract reference.1

Input fieldMeaning and unitsAccepted input
parentDivisionAtParent Division AtRequired. Finite number.
childDivisionAtChild Division AtRequired. Finite number.
suppliedReferenceIntervalSupplied Reference IntervalRequired. Finite number; minimum 0.
Output fieldInterpretationReturned shape
generationIntervalGeneration IntervalRequired. Finite number.
intervalGapInterval GapRequired. Finite number.
json
{
  "input": {
    "parentDivisionAt": 2,
    "childDivisionAt": 8,
    "suppliedReferenceInterval": 5
  },
  "output": {
    "generationInterval": 6,
    "intervalGap": 1
  }
}

Limitations and assumptions

  • Use common time coordinates; parent/child identity and cell-cycle interpretation are supplied.
  • Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
  • Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.

Alternative or Complementary methods

Review the original biological evidence and its staging or lineage model before drawing mechanistic conclusions.

References

  1. Calculation and input contract: developmental-biology/lineage-division-interval-gap — tool.io

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