Description
Return analyte amount on a supplied matrix reporting basis.
Biomarker normalization changes the reporting basis, for example from sample volume to creatinine, lipid mass, moles or matrix quantity. The numerator, denominator and conversion factors must describe compatible quantities; normalization does not by itself establish exposure, toxicity or clinical meaning.
Return analyte amount on a supplied matrix reporting basis.
When to use this tool
Use Analyte Matrix Basis Factor when converting or comparing the stated analytical reporting basis.
How to use the tool and how it works
- Enter amount, matrixAmount, reportingBasis. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read normalizedAmount. Use the output convention below.
Return analyte amount on a supplied matrix reporting basis. Require matrixAmount and reportingBasis > 0; normalizedAmount = amount*reportingBasis/matrixAmount.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| amount | Amount | Required. Finite number. |
| matrixAmount | Matrix Amount | Required. Finite number; strictly above 0. |
| reportingBasis | Reporting Basis | Required. Finite number; strictly above 0. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| normalizedAmount | Normalized Amount | Required. Finite number. |
{
"input": {
"amount": 12,
"matrixAmount": 3,
"reportingBasis": 10
},
"output": {
"normalizedAmount": 40
}
}Limitations and assumptions
- Matrix and reporting quantities must share units; the result does not identify an analyte or validate an exposure measurement.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Verify units, matrix identity, method calibration and the intended normalization model before making exposure or health inferences.
References
Similar or alternative tools
- Assay Lipid Basis Reference Factor
Convert wet-basis concentration to lipid basis and reference composition.
- Biomarker Creatinine Unit Base Flag
Return analyte per converted creatinine basis.