Thermal Death Time TDT at Given Temp Recorder
Record first tested no-detection hold at actual fixed temperature; interval-censored endpoint, not a complete kill curve or sterilization approval.
Description
Thermal Death Time TDT at Given Temp Recorder: return temperature c, observed first no detection minutes, no detection observed, actual sterility established.
Thermal death time is a duration observed at a specified temperature and under a particular detection method. A first negative observation is limited by the sampling schedule.
This tool returns temperature c, observed first no detection minutes, no detection observed, actual sterility established. Use the stated units and model convention when interpreting these fields.
When to use this tool
Use this tool when the supplied inputs match the specific operation described above and you need a repeatable result under its stated convention.
- Check the supported input and output contract against an existing calculation or observation.
- Use the complete example to confirm units, selector spelling and result interpretation.
How to use the tool and how it works
- Enter every field in the input table using the stated units and the exact supported selector spelling where applicable.
- Run the tool. Correct input errors before interpreting an output.
- Read the result fields below; use accompanying flags and the stated sign, boundary or model convention when interpreting a number.
Require matched observations at strictly increasing nonnegative times and binary detection flags that never rise after falling. With valid controls, report the first time whose flag is zero; otherwise report no detection observed as false.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| exposureMinutes | Exposure minutes. Minutes. | List of finite numbers |
| viableDetectedFlags | Viable detected flags. | List of finite numbers |
| temperatureC | Temperature c. | Finite number |
| callerControlsValid | Whether the caller has independently established that the supplied control observations are valid. | true or false |
| Output field | Interpretation |
|---|---|
| result | Object containing the following named result fields. |
| result.temperatureC | Temperature c; use the stated units and sign convention. |
| result.observedFirstNoDetectionMinutes | First qualifying time; zero is a placeholder when noDetectionObserved is false. |
| result.noDetectionObserved | True only when controls are valid and an explicit zero detection flag was supplied. |
| result.actualSterilityEstablished | Always false; a recorded lack of detection does not establish actual sterility. |
{
"input": {
"exposureMinutes": [
0,
10,
20
],
"viableDetectedFlags": [
1,
1,
0
],
"temperatureC": 70,
"callerControlsValid": true
},
"output": {
"result": {
"temperatureC": 70,
"observedFirstNoDetectionMinutes": 20,
"noDetectionObserved": true,
"actualSterilityEstablished": false
}
}
}Limitations and assumptions
- The numeric zero is a placeholder when no valid negative observation exists. Read noDetectionObserved; actualSterilityEstablished is always false.
- Every declared field is required and unexpected fields are rejected. Numeric inputs must be finite; input errors are distinct from a valid false result or an explicitly qualified output.
- Extremely large inputs and nonfinite or excessively large outputs are rejected. List positions reported by the tool use zero-based indices unless stated otherwise.
Alternative or Complementary methods
Check the underlying observations, units and conventions independently before using the result in a larger workflow. The tools listed below address nearby tasks; compare their inputs and scope before substituting one for this operation.
References
Similar or alternative tools
- Thermal Death Point Record Entry Checker
Record lowest tested no-detection temperature at actual fixed hold under valid controls; detection limit/censoring not proof of all-cell death.
- thermal f0 profile integral
Equivalent-reference thermal exposure sums temperature-dependent lethality over time.