Thermal Death Point Record Entry Checker

Record lowest tested no-detection temperature at actual fixed hold under valid controls; detection limit/censoring not proof of all-cell death.

Description

Thermal Death Point Record Entry Checker: return all controls valid, observed first no detection temperature c, no detection observed, actual sterility established.

A thermal death-point record compares detection results across tested temperatures at a fixed hold time. The tested temperatures bound what was actually observed.

This tool returns all controls valid, observed first no detection temperature c, no detection observed, actual sterility established. Use the stated units and model convention when interpreting these fields.

When to use this tool

Use this tool when the supplied inputs match the specific operation described above and you need a repeatable result under its stated convention.

  • Check the supported input and output contract against an existing calculation or observation.
  • Use the complete example to confirm units, selector spelling and result interpretation.

How to use the tool and how it works

  1. Enter every field in the input table using the stated units and the exact supported selector spelling where applicable.
  2. Run the tool. Correct input errors before interpreting an output.
  3. Read the result fields below; use accompanying flags and the stated sign, boundary or model convention when interpreting a number.

Require increasing temperatures, a positive hold time and matching binary detection flags that never return to one after zero. If controls are valid, report the first temperature with no detection.1

Input fieldMeaning and unitsAccepted input
testedTemperaturesCTested temperatures c.List of finite numbers
viableDetectedFlagsViable detected flags.List of finite numbers
holdMinutesHold minutes. Minutes.Finite number; greater than zero
callerControlsValidWhether the caller has independently established that the supplied control observations are valid.true or false
Output fieldInterpretation
resultObject containing the following named result fields.
result.allControlsValidAll controls valid flag under the exact conditions described above.
result.observedFirstNoDetectionTemperatureCFirst qualifying temperature; zero is a placeholder when noDetectionObserved is false.
result.noDetectionObservedTrue only when controls are valid and an explicit zero detection flag was supplied.
result.actualSterilityEstablishedAlways false; a recorded lack of detection does not establish actual sterility.
json
{
  "input": {
    "testedTemperaturesC": [
      60,
      70,
      80
    ],
    "viableDetectedFlags": [
      1,
      0,
      0
    ],
    "holdMinutes": 10,
    "callerControlsValid": true
  },
  "output": {
    "result": {
      "allControlsValid": true,
      "observedFirstNoDetectionTemperatureC": 70,
      "noDetectionObserved": true,
      "actualSterilityEstablished": false
    }
  }
}

Limitations and assumptions

  • Read noDetectionObserved before interpreting the numeric result. A first negative test is not proof of absolute sterility.
  • Every declared field is required and unexpected fields are rejected. Numeric inputs must be finite; input errors are distinct from a valid false result or an explicitly qualified output.
  • Extremely large inputs and nonfinite or excessively large outputs are rejected. List positions reported by the tool use zero-based indices unless stated otherwise.

Alternative or Complementary methods

Check the underlying observations, units and conventions independently before using the result in a larger workflow. The tools listed below address nearby tasks; compare their inputs and scope before substituting one for this operation.

References

  1. Tool behavior and example: Thermal Death Point Record Entry Checker — tool.io

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