Diabetic Pet Glucose Curve Tool

Actual diabetic-pet glucose curve sampled nadir/ties and piecewise-linear exposure, caller same-unit concentration. No insulin starting/titration dose, clinical target, continuous unsampled nadir or safe glycemia approval.

Description

A sampled glucose curve records concentrations at documented times.

A sampled glucose curve records concentrations at documented times.1

Trapezoidal exposure, a time-weighted mean and sampled nadir describe that record rather than unobserved glycemic behavior.

When to use Diabetic Pet Glucose Curve Tool

Use this tool to calculate or review the supplied observations under the stated rules. Establish the animal, measurement protocol, units and independently applicable veterinary prescription or reference.

How to use Diabetic Pet Glucose Curve Tool and understand its results

  1. Establish the animal, measurement protocol, units and independently applicable veterinary prescription or reference.
  2. Enter independentlyRecordedGlucoseTimesHours, independentlyMeasuredGlucoseConcentrations, using the field meanings and rules below, then run the tool.
  3. Read result.observedTrapezoidalGlucoseExposure, result.observedTimeWeightedGlucoseMean, result.observedGlucoseNadir, result.observedNadirTimesHours. Use the units and subtraction order below to interpret each value; retain negative differences where returned.
  4. Correct any reported input issue and run again. Before using a successful result, check the stated units, signs, reference scope and observation coverage.
Input fieldMeaningValue typeRequirement
independentlyRecordedGlucoseTimesHoursIndependently recorded glucose times hourslist of numberRequired
independentlyMeasuredGlucoseConcentrationsIndependently measured glucose concentrationslist of numberRequired

Require at least two aligned finite sample times in strictly increasing order and nonnegative glucose concentrations. Negative time coordinates are allowed. Sum trapezoids between samples and divide by the first-to-last time span for the time-weighted mean. Return the minimum sampled glucose and every time tied at that minimum, in order. No value outside the observed window is inferred.

area=Σ((t_(i+1)−t_i)×(g_i+g_(i+1))/2); mean=area/(t_last−t_first); nadir=min(g)

Use the matching field units and the exact boundary, ordering and reference rules above.

Output fieldMeaningValue type
resultQualified observation, conditional calculation or referenceobject
result.observedTrapezoidalGlucoseExposureTrapezoidal concentration-time area over the supplied sample window.number
result.observedTimeWeightedGlucoseMeanTrapezoidal glucose area divided by the observed first-to-last time span.number
result.observedGlucoseNadirMinimum glucose among the supplied samples, in their concentration units.number
result.observedNadirTimesHoursEvery sample time tied for the minimum recorded glucose, in supplied order.list
json
{
  "input": {
    "independentlyRecordedGlucoseTimesHours": [
      0,
      2,
      4
    ],
    "independentlyMeasuredGlucoseConcentrations": [
      100,
      200,
      100
    ]
  },
  "output": {
    "result": {
      "observedTrapezoidalGlucoseExposure": 600,
      "observedTimeWeightedGlucoseMean": 150,
      "observedGlucoseNadir": 100,
      "observedNadirTimesHours": [
        0,
        4
      ]
    }
  }
}

Limitations and assumptions

The patient context, observations and applicability of any reference or prescription must be independently established. This result supplies no diagnosis, default dose, treatment selection or assessment of clinical suitability.

Missing required fields, unknown fields, wrong types and violated rules return input issues. Numeric values and outputs must be finite. Lists and matrices must be dense, without missing cells. Numeric lists allow at most 10000 entries, subject to the narrower lengths and code rules above. Extremely large composite outputs are rejected.

Alternative or Complementary methods

For a related step, use Dog Insulin Starting Dose Calculator: An insulin prescription uses units of activity, while a product concentration expresses units per millilitre. For a complementary comparison, use Cat Insulin Starting Dose Calculator: A cat insulin prescription and product concentration use activity units rather than a generic drug mass.

References

  1. Diabetic Pet Glucose Curve Tool — tool.io

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