Unit Risk Calculator
Empirical risk-screen/concentration unit-risk coefficient extraction, not assigning toxic potency from one unvalidated exposure scenario. Actual independently matched quantities/units required; not infer causal effect, clinical guidance or safe design.
Description
A unit-risk coefficient relates a specified excess-risk screen to its matched concentration basis.
When to use Unit Risk Calculator
Use this tool to calculate or review the supplied observations under the stated rules. Establish the chemical, exposure route, endpoint, measurement basis and independently applicable assay or assessment reference.
How to use Unit Risk Calculator and understand its results
- Establish the chemical, exposure route, endpoint, measurement basis and independently applicable assay or assessment reference.
- Enter callerIndependentlyEstablishedExcessRiskScreen, matchedIndependentlyAssessedConcentration, using the field meanings and rules below, then run the tool.
- Read result.observedRatio. Use the units and subtraction order below to interpret each value; retain negative differences where returned.
- Correct any reported input issue and run again. Before using a successful result, check the stated units, signs, reference scope and observation coverage.
| Input field | Meaning | Value type | Requirement |
|---|---|---|---|
| callerIndependentlyEstablishedExcessRiskScreen | Caller independently established excess risk screen | number | Required |
| matchedIndependentlyAssessedConcentration | Matched independently assessed concentration | number | Required |
Require a finite nonnegative numerator and strictly positive denominator. Divide the supplied measurements without converting their units or clamping the result. The implementation does not enforce numerator≤denominator, so a ratio above one can be returned. Use independently compatible definitions and units.
observedRatio=numerator/denominator Use the matching field units and the exact boundary, ordering and reference rules above.
| Output field | Meaning | Value type |
|---|---|---|
| result | Qualified observed calculation or explicit reference | object |
| result.observedRatio | Independently established risk screen divided by matched concentration, in reciprocal-concentration units. | number |
{
"input": {
"callerIndependentlyEstablishedExcessRiskScreen": 2,
"matchedIndependentlyAssessedConcentration": 4
},
"output": {
"result": {
"observedRatio": 0.5
}
}
}Limitations and assumptions
Chemical identity, route, assay, exposure basis and reference applicability are caller-established. The output supplies no causal conclusion, universal toxicity threshold or authoritative regulatory determination.
Missing required fields, unknown fields, wrong types and violated rules return input issues. Numeric values and outputs must be finite. Extremely large composite outputs are rejected.
Alternative or Complementary methods
For a related step, use Inhalation Unit Risk Calculator: An inhalation unit-risk coefficient uses a specified long-term air-concentration basis. For a complementary comparison, use Inhalation Slope Factor Calculator: An inhalation slope coefficient depends on a defined inhaled-dose metric and matched risk assessment.
References
-
Unit Risk Calculator — tool.io
-
IRIS glossary: unit risk — United States Environmental Protection Agency
Similar or alternative tools
- Inhalation Unit Risk Calculator
An inhalation unit-risk coefficient uses a specified long-term air-concentration basis.
- Inhalation Slope Factor Calculator
An inhalation slope coefficient depends on a defined inhaled-dose metric and matched risk assessment.