Attributable Risk Calculator
Actual independently qualified exposed-versus-unexposed risk difference and difference/exposed-risk fraction. Causal attribution, confounding and compatible populations external; negative results retained, not predicted toxic harm.
Description
An exposed-versus-unexposed risk difference compares matched population response fractions.
An exposed-versus-unexposed risk difference compares matched population response fractions.1
Calling the metric attributable does not independently establish causal attribution.
When to use Attributable Risk Calculator
Use this tool to calculate or review the supplied observations under the stated rules. Establish the chemical, exposure route, endpoint, measurement basis and independently applicable assay or assessment reference.
How to use Attributable Risk Calculator and understand its results
- Establish the chemical, exposure route, endpoint, measurement basis and independently applicable assay or assessment reference.
- Enter actualIndependentlyAssessedExposedRisk, actualMatchedUnexposedRisk, using the field meanings and rules below, then run the tool.
- Read result.signedObservedAttributableRisk, result.conditionalExposedAttributableFraction. Use the units and subtraction order below to interpret each value; retain negative differences where returned.
- Correct any reported input issue and run again. Before using a successful result, check the stated units, signs, reference scope and observation coverage.
| Input field | Meaning | Value type | Requirement |
|---|---|---|---|
| actualIndependentlyAssessedExposedRisk | Actual independently assessed exposed risk | number | Required |
| actualMatchedUnexposedRisk | Actual matched unexposed risk | number | Required |
Require exposed response in (0,1] and unexposed response in [0,1]. Return exposed-minus-unexposed difference and that difference divided by exposed response. Both may be negative; this arithmetic does not establish causation or control confounding.
difference=exposedResponse−unexposedResponse; attributableFraction=difference/exposedResponse Use the matching field units and the exact boundary, ordering and reference rules above.
| Output field | Meaning | Value type |
|---|---|---|
| result | Qualified observed calculation or explicit reference | object |
| result.signedObservedAttributableRisk | Exposed response fraction minus unexposed response fraction. | number |
| result.conditionalExposedAttributableFraction | Exposed-minus-unexposed difference divided by exposed risk; signed fraction, not percent. | number |
{
"input": {
"actualIndependentlyAssessedExposedRisk": 0.3,
"actualMatchedUnexposedRisk": 0.1
},
"output": {
"result": {
"signedObservedAttributableRisk": 0.19999999999999998,
"conditionalExposedAttributableFraction": 0.6666666666666666
}
}
}Limitations and assumptions
Chemical identity, route, assay, exposure basis and reference applicability are caller-established. The output supplies no causal conclusion, universal toxicity threshold or authoritative regulatory determination.
Missing required fields, unknown fields, wrong types and violated rules return input issues. Numeric values and outputs must be finite. Extremely large composite outputs are rejected.
Alternative or Complementary methods
For a related step, use Extra Risk Calculator: Extra risk adjusts an observed response difference for the fraction without the background response. For a complementary comparison, use Added Risk Calculator: Added risk is the signed difference between matched response and background risk fractions.
References
-
Attributable Risk Calculator — tool.io
Similar or alternative tools
- Extra Risk Calculator
Extra risk adjusts an observed response difference for the fraction without the background response.
- Added Risk Calculator
Added risk is the signed difference between matched response and background risk fractions.