Spinal Cord Area C2 Calculator

Actual matched C2cord-mask slice areas pooled by independently represented weights. C2landmark/mask, oblique-plane correction and pixel calibration external, not cord volume or clinical diagnosis.

Description

C2 spinal-cord cross-sectional area depends on independently qualified segmentation and pixel calibration.

C2 spinal-cord cross-sectional area depends on independently qualified segmentation and pixel calibration.1

A weighted slice average differs from a cord volume.

When to use Spinal Cord Area C2 Calculator

Use this tool to calculate or review the supplied observations under the stated rules. Establish the assessment or recording protocol, units, instrument version and independently applicable reference or calibration.

How to use Spinal Cord Area C2 Calculator and understand its results

  1. Establish the assessment or recording protocol, units, instrument version and independently applicable reference or calibration.
  2. Enter independentlyC2SegmentedPixelCountsBySlice, verifiedPixelAreaSquareMm, representedSliceWeights, using the field meanings and rules below, then run the tool.
  3. Read result.observedWeightedC2CrossSectionalAreaSquareMm. Use the units and sign conventions below.
  4. Correct any reported input issue and run again. Before using a successful result, check the stated units, signs, reference scope and observation coverage.
Input fieldMeaningValue typeRequirement
independentlyC2SegmentedPixelCountsBySliceIndependently c2 segmented pixel counts by slicelist of numberRequired
verifiedPixelAreaSquareMmVerified pixel area square mmnumberRequired
representedSliceWeightsRepresented slice weightslist of numberRequired

Require nonempty aligned integer segmented pixel counts 0–100000000 and nonnegative represented slice weights with positive total weight. Pixel area must be positive square millimeters. Multiply weighted mean pixel count by pixel area; no slice-thickness multiplication is performed.

weightedAreaMm2=pixelAreaMm2×Σ(pixelCount_i×weight_i)/Σweight_i

Use the matching field units and the exact boundary, ordering and reference rules above.

Output fieldMeaningValue type
resultStructured result; its nested fields below contain the actual calculation or selected referenceobject
result.observedWeightedC2CrossSectionalAreaSquareMmObserved Weighted C2 Cross Sectional Area Square Mmnumber
json
{
  "input": {
    "independentlyC2SegmentedPixelCountsBySlice": [
      100,
      120
    ],
    "verifiedPixelAreaSquareMm": 1,
    "representedSliceWeights": [
      1,
      1
    ]
  },
  "output": {
    "result": {
      "observedWeightedC2CrossSectionalAreaSquareMm": 110
    }
  }
}

Limitations and assumptions

Actual acquisition, assessment protocol, instrument version and calibration determine applicability. The tool does not examine a person, classify images, administer a questionnaire or choose diagnostic cutoffs.

Missing required fields, unknown fields, wrong types and violated rules return input issues. Numeric values and outputs must be finite. Lists and matrices must be dense, without missing cells. Numeric lists allow at most 10000 entries; ordinary string lists allow at most 128 strings of 128 UTF-16 units each; numeric matrices allow at most 128 rows and 128 columns, subject to narrower requirements above. Extremely large composite outputs are rejected.

Alternative or Complementary methods

For a related step, use Average Cortical Thickness Calculator: Mean cortical thickness can weight vertex measurements by represented surface area. For a complementary comparison, use Thalamic Subcortical Volume Calculator: Bilateral thalamic volume combines independently segmented left and right measurements.

References

  1. Spinal Cord Area C2 Calculator — tool.io

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