Driving Force Calculator
Signed membrane electrical driving force Vm−Erev, not net Goldman potential or Nernstconcentrationmodel. Actual independently matched observations/units and protocol, not diagnosis, causal mechanism, clinical decision or validated individual prediction.
Description
Electrical driving force is the signed difference between membrane potential and an independently established reversal potential.
Electrical driving force is the signed difference between membrane potential and an independently established reversal potential.1
This tool calculates that voltage difference without fitting ion concentrations or predicting current.
When to use Driving Force Calculator
This tool calculates that voltage difference without fitting ion concentrations or predicting current.
How to use Driving Force Calculator and how it works
- Prepare signed membrane potential mv, independent reversal potential mv, using the input definitions and matching units below.
- Enter the required fields and run Driving Force Calculator.
- Read result.value using the units, signs and ordering explained below.
- Correct any rejected inputs and rerun; interpret the result within the stated model and its assumptions.
| Input field | Meaning | Value type | Requirement |
|---|---|---|---|
| actualSignedMembranePotentialMv | Actual Signed Membrane Potential Mv. Use the units and matching context stated in the calculation below. | number | Required; finite; other constraints below |
| callerIndependentReversalPotentialMv | Caller Independent Reversal Potential Mv. Use the units and matching context stated in the calculation below. | number | Required; finite; other constraints below |
Accept finite signed membrane and independently established reversal potentials in mV. Return membrane minus reversal as signed mV. No conductance or ion-concentration model is evaluated.
drivingForceMv=membraneMv-reversalMv Apply the input ordering, units and branch conditions stated above.
| Output field | Meaning | Value type |
|---|---|---|
| result | Object containing the calculated or selected fields below. | object |
| result.value | Signed voltage difference in mV. | number |
{
"input": {
"actualSignedMembranePotentialMv": -60,
"callerIndependentReversalPotentialMv": -70
},
"output": {
"result": {
"value": 10
}
}
}Limitations and assumptions
The calculation uses the supplied observations and model inputs. It does not collect measurements, select a reference population or coefficient, or establish that the model applies to the actual case. The stated branch conditions and output units remain part of the result.
All fields require explicit values. Unexpected fields, wrong types, nonfinite numbers and sparse arrays are rejected. Alignment, bounds and supported-token rules are explained above; extremely large inputs or nonfinite results can also fail. Input errors differ from successful false comparisons, unavailable-domain flags and empty match lists.
Alternative or Complementary methods
Use Synaptic Cleft Width Calculator for a complementary operation: A microscopic width measurement requires a calibration that applies to the image being measured.
Use Low Threshold Spike Amplitude Calculator for a complementary operation: A low-threshold spike amplitude requires independently identified peak and baseline values on the same voltage basis.
References
-
Driving Force Calculator — tool.io
Similar or alternative tools
- Synaptic Cleft Width Calculator
A microscopic width measurement requires a calibration that applies to the image being measured.
- Low Threshold Spike Amplitude Calculator
A low-threshold spike amplitude requires independently identified peak and baseline values on the same voltage basis.