Intracranial Brain Volume Calculator

Actual disjoint complete GM/WM/CSF segmentation partition sum in mL. Segmentation, mask inclusion and compatibility external; not identify anatomy or infer disease or true intracranial volume from incomplete masks.

Description

An intracranial volume partition combines independently segmented gray matter, white matter and CSF.

An intracranial volume partition combines independently segmented gray matter, white matter and CSF.1

Addition assumes the supplied partitions are disjoint and appropriately complete.

When to use Intracranial Brain Volume Calculator

Use this tool to calculate or review the supplied observations under the stated rules. Establish the assessment or recording protocol, units, instrument version and independently applicable reference or calibration.

How to use Intracranial Brain Volume Calculator and understand its results

  1. Establish the assessment or recording protocol, units, instrument version and independently applicable reference or calibration.
  2. Enter independentlySegmentedGrayMatterVolumeMl, independentlySegmentedWhiteMatterVolumeMl, independentlySegmentedCsfVolumeMl, using the field meanings and rules below, then run the tool.
  3. Read result.observedPartitionedIntracranialVolumeMl. Use the units and sign conventions below.
  4. Correct any reported input issue and run again. Before using a successful result, check the stated units, signs, reference scope and observation coverage.
Input fieldMeaningValue typeRequirement
independentlySegmentedGrayMatterVolumeMlIndependently segmented gray matter volume mlnumberRequired
independentlySegmentedWhiteMatterVolumeMlIndependently segmented white matter volume mlnumberRequired
independentlySegmentedCsfVolumeMlIndependently segmented csf volume mlnumberRequired

Require nonnegative gray-matter, white-matter and CSF volume in milliliters. Sum these three declared partitions without verifying segmentation or disjointness.

partitionedIntracranialMl=grayMatterMl+whiteMatterMl+CSFMl

Use the matching field units and the exact boundary, ordering and reference rules above.

Output fieldMeaningValue type
resultStructured result; its nested fields below contain the actual calculation or selected referenceobject
result.observedPartitionedIntracranialVolumeMlObserved Partitioned Intracranial Volume Mlnumber
json
{
  "input": {
    "independentlySegmentedGrayMatterVolumeMl": 500,
    "independentlySegmentedWhiteMatterVolumeMl": 400,
    "independentlySegmentedCsfVolumeMl": 100
  },
  "output": {
    "result": {
      "observedPartitionedIntracranialVolumeMl": 1000
    }
  }
}

Limitations and assumptions

Actual acquisition, assessment protocol, instrument version and calibration determine applicability. The tool does not examine a person, classify images, administer a questionnaire or choose diagnostic cutoffs.

Missing required fields, unknown fields, wrong types and violated rules return input issues. Numeric values and outputs must be finite. Extremely large composite outputs are rejected.

Alternative or Complementary methods

For a related step, use White Matter Fraction Calculator: White-matter fraction expresses a segmented volume relative to a matched intracranial volume. For a complementary comparison, use Gray Matter Fraction Calculator: Gray-matter fraction compares a segmented gray-matter volume with matched intracranial volume.

References

  1. Intracranial Brain Volume Calculator — tool.io

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