Carryover Residual
Measure blank-after-high calibrator carryover percentage.
Description
Carryover screening compares a blank response with a preceding high-standard response.
Carryover screening compares a blank response with a preceding high-standard response. A caller maximum defines the residual gate.1
Measure blank-after-high calibrator carryover percentage.
When to use Carryover Residual
Use this tool to measure blank-after-high calibrator carryover percentage.
Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
How to use Carryover Residual and understand its results
- Prepare the measured profile, formula counts, upstream model outputs or caller-defined reference criteria requested. Keep paired entries aligned and units, sample basis and preprocessing consistent.
- Enter blankAfterHighArea, highCalibratorArea, maximumCarryoverPercent using the field table and calculation rules, then run the tool.
- Read carryoverPercent, exceedsLimit. The explanation below defines the units, signs, ordering and any flags or placeholder values.
- If the tool reports an input issue, correct the values and run it again. Apply the stated assumptions when interpreting a successfully returned result.
| Input field | Meaning | Value type; see rules below | Requirement |
|---|---|---|---|
| blankAfterHighArea | Blank after high area | number | Required |
| highCalibratorArea | High calibrator area | number | Required |
| maximumCarryoverPercent | Maximum carryover percent | number | Required |
Enter nonnegative blank, positive high-standard area and finite maximum percentage. Return percentage and strict exceedance flag; equality is unflagged.
carryover%=100 blank/high; flagged=carryover%>maximum Units, indexing, boundary conditions and exceptional cases are defined in the calculation rules above.
| Output field | Meaning | Value type |
|---|---|---|
| carryoverPercent | Carryover percent | number |
| exceedsLimit | Exceeds limit | boolean |
{
"input": {
"blankAfterHighArea": 2,
"highCalibratorArea": 100,
"maximumCarryoverPercent": 1
},
"output": {
"carryoverPercent": 2,
"exceedsLimit": true
}
}Limitations and assumptions
The maximum may be negative. No injection sequence, analyte assignment or method acceptance standard is checked.
Numeric inputs must be finite. Follow the calculation-specific rules for overflow, underflow and exceptional cases. Missing required fields, extra fields, wrong value types and violations of the calculation rules are input errors. A successfully returned false flag is an evaluated outcome; its meaning is explained above.
Alternative or Complementary methods
Use Blank Fold Filter: Filter features by sample-to-blank peak-area ratio. For a complementary task, use Pooled QC Cv Gate: Gate pooled metabolomics QC by coefficient of variation.
References
-
Carryover Residual — tool.io
Similar or alternative tools
- Blank Fold Filter
Filter features by sample-to-blank peak-area ratio.
- Pooled QC Cv Gate
Gate pooled metabolomics QC by coefficient of variation.