Description
Sum callable opportunities and selected callable opportunity; divide or return flagged zero.
Sequence-derived quantities depend on aligned observations, callable sites and a stated substitution or codon model. A count ratio or one site's opportunity is distinct from a corrected evolutionary distance or statistical evidence of selection.
Sum callable opportunities and selected callable opportunity; divide or return flagged zero.
When to use this tool
Use Codon Site Opportunity Share when you need the stated sequence-distance or codon-opportunity term.
How to use the tool and how it works
- Enter opportunities, callableSites, selectedSite. Keep parallel arrays aligned. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read callableOpportunity, selectedOpportunity, share, defined. Inspect defined before interpreting the associated values.
Require exactly three nonnegative opportunities and three callable flags, plus zero-based selectedSite 0-2. Sum callable opportunities and selected callable opportunity; divide or return flagged zero.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| opportunities | Opportunities | Required. Array of finite number; minimum 0; maximum items 256. |
| callableSites | Callable Sites | Required. Array of boolean; maximum items 256. |
| selectedSite | Selected Site | Required. Safe integer; minimum 0; maximum 2. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| callableOpportunity | Callable Opportunity | Required. Finite number. |
| selectedOpportunity | Selected Opportunity | Required. Finite number. |
| share | Dimensionless share on the numerator and denominator basis stated above. | Required. Finite number. |
| defined | Whether the stated denominator or normalization exists; inspect before interpreting a zero placeholder. | Required. Boolean. |
{
"input": {
"opportunities": [
0.5,
1,
0.5
],
"callableSites": [
true,
true,
false
],
"selectedSite": 0
},
"output": {
"callableOpportunity": 1.5,
"selectedOpportunity": 0.5,
"share": 0.3333333333333333,
"defined": true
}
}Limitations and assumptions
- The denominator is callable opportunity weight, not three sites or total opportunity including uncallable positions. No alignment, codon model or standard genetic code is validated.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use a complete sequence-analysis method with an appropriate alignment, genetic code and model. Review gaps, missingness, multiple substitutions, saturation and uncertainty before biological interpretation.
References
Similar or alternative tools
- Codon Synonymous Site Mask
Mark neighbors matching its nonexcluded amino-acid token and sum their weights by changed position and overall.
- Codon Sites Zero Denominator Tool
One supplied change/site ratio with zero support flagged; no substitution model or dN/dS estimator.