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Metabolic Reaction Direction Sign

Apply an explicit forward-positive sign convention to a nonnegative recorded metabolic reaction-rate magnitude.

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Description

Apply a supplied metabolic reaction direction to a nonnegative magnitude.

Computational biology models distinguish counts, rates, reaction orders, stoichiometric signs and state constraints. A volume-scaling factor is only one component of a stochastic propensity, and a supplied flux bound is separate from a feasible network solution. Bookkeeping balances do not infer unobserved biological states or validate a model.

Apply a supplied metabolic reaction direction to a nonnegative magnitude.

When to use this tool

Use Metabolic Reaction Direction Sign when you already have rateMagnitude, direction and need to apply a supplied metabolic reaction direction to a nonnegative magnitude.

How to use the tool and how it works

  1. Enter rateMagnitude, direction. Use the units and conventions below.
  2. Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
  3. Read signedRate. Use the output convention below.

Require magnitude>=0 and direction forward/reverse/zero; zero direction requires magnitude=0. Negate for reverse, otherwise preserve magnitude.1

Input fieldMeaning and unitsAccepted input
rateMagnitudeRate MagnitudeRequired. Finite number; minimum 0.
directionLiteral forward/reverse/zero convention; zero direction requires zero rateMagnitude.Required. Text; one of "forward", "reverse", "zero"; maximum UTF-16 length 8192.
Output fieldInterpretationReturned shape
signedRateSigned RateRequired. Finite number.
json
{
  "input": {
    "rateMagnitude": 3,
    "direction": "reverse"
  },
  "output": {
    "signedRate": -3
  }
}

Limitations and assumptions

  • Forward/reverse with zero magnitude are allowed. No reaction, thermodynamic direction, unit basis or biological flux is inferred.
  • Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
  • Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.

Alternative or Complementary methods

Check the full model definition, data provenance, reaction conventions and numerical implementation. Use complete network, stochastic or population analyses when needed; local count balances, priorities and bound checks cannot establish biological mechanisms or model adequacy.

References

  1. Calculation and input contract: computational-biology/metabolic-reaction-direction-sign — tool.io

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