Analytical Spike Recovery
Calculate percent recovery as (measured spiked result − unspiked result)/known spike amount ×100. All three quantities must use the same unit; values outside 0–100% can reveal matrix effects or measurement problems.
Description
Calculate percent recovery as (measured spiked result − unspiked result)/known spike amount ×100. All three quantities must use the same unit; values outside 0–100% can reveal matrix effects or measurement problems.
Analytical Spike Recovery is a focused chemistry tool that calculate percent recovery as (measured spiked result − unspiked result)/known spike amount ×100. All three quantities must use the same unit; values outside 0–100% can reveal matrix effects or measurement problems. It calculates locally from the values you enter and exposes the result without changing the source observations.1
When to use Analytical Spike Recovery
Use Analytical Spike Recovery when you need to calculate percent recovery as (measured spiked result − unspiked result)/known spike amount ×100. All three quantities must use the same unit; values outside 0–100% can reveal matrix effects or measurement problems. Enter Unspiked measured amount, Spiked measured amount, and Known added amount using the definitions and units below so the result can be reproduced.
- Unspiked measured amount
- A finite measured or assumed value.
- Spiked measured amount
- A finite measured or assumed value.
- Known added amount
- A finite measured or assumed value greater than or equal to 5e-324.
How Analytical Spike Recovery calculates the result
The published tool contract uses this rule: Calculate percent recovery as (measured spiked result − unspiked result)/known spike amount ×100. All three quantities must use the same unit; values outside 0–100% can reveal matrix effects or measurement problems.1
- Recovery Percent
- The calculated recovery percent.
Limitations of Analytical Spike Recovery
A ratio or percentage can conceal the scale of its numerator and denominator and becomes sensitive to measurement error when the denominator is small.
Alternative or Complementary measurements
Retain the original Unspiked measured amount, Spiked measured amount, and Known added amount values and their units alongside the result. Analytical Relative Standard Deviation is useful when you instead need to calculate relative standard deviation from a supplied sample standard deviation and mean: RSD%=100s/|mean|. The mean cannot be zero; this is a precision measure, not an accuracy estimate. Standardization Factor Calculator provides another view by helping you calculate an analytical standardization factor as actual concentration divided by nominal concentration.
References
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Analytical chemistry — Wikipedia contributors
Similar or alternative tools
- Analytical Relative Standard Deviation
Calculate relative standard deviation from a supplied sample standard deviation and mean: RSD%=100s/|mean|. The mean cannot be zero; this is a precision measure, not an accuracy estimate.
- Standardization Factor Calculator
Calculate an analytical standardization factor as actual concentration divided by nominal concentration.
- Calibration Intercept
Compute the calibration curve intercept from the low calibration point and the slope.