Description
Calculate supplied open/closed dwell cycle duration and open fraction.
Biophysical scalar models require explicit signal, concentration, temperature, energy and geometric conventions. Effective concentration differs from dimensionless activity, a single displacement differs from mean-square displacement, and a fluorescence yield ratio needs absorption and refractive-index corrections. Supplied model parameters do not establish that the model applies to an experiment.
Calculate supplied open/closed dwell cycle duration and open fraction.
When to use this tool
Use Channel Open Closed Dwell Pair when you already have openDwell, closedDwell and need to calculate supplied open/closed dwell cycle duration and open fraction.
How to use the tool and how it works
- Enter openDwell, closedDwell. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read cycleDuration, openFraction. Use the output convention below.
Require both durations>=0 with positive sum; return sum and open/sum.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| openDwell | Open Dwell | Required. Finite number; minimum 0. |
| closedDwell | Closed Dwell | Required. Finite number; minimum 0. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| cycleDuration | openDwell+closedDwell, required positive and finite. | Required. Finite number. |
| openFraction | Open Fraction | Required. Finite number. |
{
"input": {
"openDwell": 3,
"closedDwell": 9
},
"output": {
"cycleDuration": 12,
"openFraction": 0.25
}
}Limitations and assumptions
- Matching time bases are assumed. No channel, event, kinetics, stationary open probability or actual dwell time is inferred.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use the complete physical model, calibrated measurements and uncertainty analysis. Check reference states, photon-signal bases, diffusion assumptions and binding-constant conventions before interpreting local contributions as physical measurements.
References
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