Ki67 Proliferation Index
Compute the Ki67 proliferation index as the percentage of Ki67-positive cells.
Description
Compute the Ki67 proliferation index as the percentage of Ki67-positive cells.
Ki67 Proliferation Index is a focused biology tool that compute the Ki67 proliferation index as the percentage of Ki67-positive cells. It calculates locally from the values you enter and exposes the result without changing the source observations.1
When to use Ki67 Proliferation Index
Use Ki67 Proliferation Index when you need to compute the Ki67 proliferation index as the percentage of Ki67-positive cells. Enter Ki67-positive cells and Total cells using the definitions and units below so the result can be reproduced.
- Ki67-positive cells
- An integer count or setting greater than or equal to 0.
- Total cells
- An integer count or setting greater than or equal to 0.
How Ki67 Proliferation Index calculates the result
The published tool contract uses this rule: Compute the Ki67 proliferation index as the percentage of Ki67-positive cells.
- Ki67 index
- The calculated ki67 index in %.
Limitations of Ki67 Proliferation Index
A ratio or percentage can conceal the scale of its numerator and denominator and becomes sensitive to measurement error when the denominator is small.
Alternative or Complementary measurements
Retain the original Ki67-positive cells and Total cells values and their units alongside the result. Mitotic Index % is useful when you instead need to calculate the mitotic index as the percentage of counted cells in mitosis. Apoptotic Index provides another view by helping you compute the apoptotic index as the ratio of apoptotic cells to mitotic cells.
References
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Proliferation marker protein Ki-67 — Wikipedia contributors
Similar or alternative tools
- Mitotic Index %
Calculate the mitotic index as the percentage of counted cells in mitosis.
- Apoptotic Index
Compute the apoptotic index as the ratio of apoptotic cells to mitotic cells.
- Phase Mitotic Fraction
Compute the fraction of cells positive for a specific mitotic phase marker.