Ki67 Proliferation Index

Compute the Ki67 proliferation index as the percentage of Ki67-positive cells.

Description

Compute the Ki67 proliferation index as the percentage of Ki67-positive cells.

Ki67 Proliferation Index is a focused biology tool that compute the Ki67 proliferation index as the percentage of Ki67-positive cells. It calculates locally from the values you enter and exposes the result without changing the source observations.1

When to use Ki67 Proliferation Index

Use Ki67 Proliferation Index when you need to compute the Ki67 proliferation index as the percentage of Ki67-positive cells. Enter Ki67-positive cells and Total cells using the definitions and units below so the result can be reproduced.

Ki67-positive cells
An integer count or setting greater than or equal to 0.
Total cells
An integer count or setting greater than or equal to 0.

How Ki67 Proliferation Index calculates the result

The published tool contract uses this rule: Compute the Ki67 proliferation index as the percentage of Ki67-positive cells.

Ki67 index
The calculated ki67 index in %.

Limitations of Ki67 Proliferation Index

A ratio or percentage can conceal the scale of its numerator and denominator and becomes sensitive to measurement error when the denominator is small.

Alternative or Complementary measurements

Retain the original Ki67-positive cells and Total cells values and their units alongside the result. Mitotic Index % is useful when you instead need to calculate the mitotic index as the percentage of counted cells in mitosis. Apoptotic Index provides another view by helping you compute the apoptotic index as the ratio of apoptotic cells to mitotic cells.

References

  1. Proliferation marker protein Ki-67 — Wikipedia contributors

Similar or alternative tools

  • Mitotic Index %

    Calculate the mitotic index as the percentage of counted cells in mitosis.

  • Apoptotic Index

    Compute the apoptotic index as the ratio of apoptotic cells to mitotic cells.

  • Phase Mitotic Fraction

    Compute the fraction of cells positive for a specific mitotic phase marker.

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