Expected Heterozygosity

Compute expected heterozygosity he = 1 - (p^2 + q^2) at a two-allele locus.

Description

Compute expected heterozygosity he = 1 - (p^2 + q^2) at a two-allele locus.

Expected Heterozygosity is a focused biology tool that compute expected heterozygosity he = 1 - (p^2 + q^2) at a two-allele locus. It calculates locally from the values you enter and exposes the result without changing the source observations.1

When to use Expected Heterozygosity

Use Expected Heterozygosity when you need to compute expected heterozygosity he = 1 - (p^2 + q^2) at a two-allele locus. Enter Allele A frequency using the definitions and units below so the result can be reproduced.

Allele A frequency
A finite measured or assumed value from 0 through 1.

How Expected Heterozygosity calculates the result

The published tool contract uses this rule: Compute expected heterozygosity he = 1 - (p^2 + q^2) at a two-allele locus.1

Expected heterozygosity
The calculated expected heterozygosity.

Limitations of Expected Heterozygosity

The calculation does not propagate measurement uncertainty, sampling error, or biological and chemical variability. Allele A frequency must remain between 0 and 1.

Alternative or Complementary measurements

Retain the original Allele A frequency values and their units alongside the result. Observed Heterozygosity is useful when you instead need to compute observed heterozygosity as the fraction of individuals that are heterozygous. Chao1 Bias Corrected provides another view by helping you compute the documented bias-corrected Chao1 estimate as observed species plus singletons times singletons minus one divided by two times doubletons plus one.

References

  1. Zygosity — Wikipedia contributors

Similar or alternative tools

  • Observed Heterozygosity

    Compute observed heterozygosity as the fraction of individuals that are heterozygous.

  • Chao1 Bias Corrected

    Compute the documented bias-corrected Chao1 estimate as observed species plus singletons times singletons minus one divided by two times doubletons plus one.

  • ACE Bias Corrected

    Estimate abundance-based species richness with ACE using the species observed at most ten times, their total individuals, singleton count, and the rare-frequency moment sum i(i-1)f_i. ACE is undefined when every rare individual is a singleton.

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