Nei Genetic Distance

Compute Nei's standard genetic distance between two populations at a two-allele locus.

Description

Compute Nei's standard genetic distance between two populations at a two-allele locus.

Nei Genetic Distance is a focused biology tool that compute Nei's standard genetic distance between two populations at a two-allele locus. It calculates locally from the values you enter and exposes the result without changing the source observations.1

When to use Nei Genetic Distance

Use Nei Genetic Distance when you need to compute Nei's standard genetic distance between two populations at a two-allele locus. Enter Population X allele 1 frequency, Population X allele 2 frequency, Population Y allele 1 frequency, and Population Y allele 2 frequency using the definitions and units below so the result can be reproduced.

Population X allele 1 frequency
A finite measured or assumed value greater than or equal to 0.
Population X allele 2 frequency
A finite measured or assumed value greater than or equal to 0.
Population Y allele 1 frequency
A finite measured or assumed value greater than or equal to 0.
Population Y allele 2 frequency
A finite measured or assumed value greater than or equal to 0.

How Nei Genetic Distance calculates the result

The published tool contract uses this rule: Compute Nei's standard genetic distance between two populations at a two-allele locus.1

Nei distance
The calculated nei distance.

Limitations of Nei Genetic Distance

The calculation does not propagate measurement uncertainty, sampling error, or biological and chemical variability.

Alternative or Complementary measurements

Retain the original Population X allele 1 frequency, Population X allele 2 frequency, Population Y allele 1 frequency, and Population Y allele 2 frequency values and their units alongside the result. Additive Variance Component is useful when you instead need to derive the additive genetic variance by subtracting dominance and epistatic components from the total genetic variance. Drift Variance provides another view by helping you compute the expected one-generation variance in allele frequency under diploid Wright-Fisher drift: p × (1 - p) / (2Ne), where Ne is the effective number of breeding individuals.

References

  1. Genetic distance — Wikipedia contributors

Similar or alternative tools

  • Additive Variance Component

    Derive the additive genetic variance by subtracting dominance and epistatic components from the total genetic variance.

  • Drift Variance

    Compute the expected one-generation variance in allele frequency under diploid Wright-Fisher drift: p × (1 - p) / (2Ne), where Ne is the effective number of breeding individuals.

  • Two-Band EVI

    Compute the two-band Enhanced Vegetation Index as 2.5 * (NIR - red) / (NIR + 2.4 * red + 1) from reflectances between zero and one, rejecting degenerate reflectances that zero the denominator.

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