Epistasis Variance Share

Express the epistatic variance component as a percentage of the total genetic variance.

Description

Express the epistatic variance component as a percentage of the total genetic variance.

Epistasis Variance Share is a focused biology tool that express the epistatic variance component as a percentage of the total genetic variance. It calculates locally from the values you enter and exposes the result without changing the source observations.1

When to use Epistasis Variance Share

Use Epistasis Variance Share when you need to express the epistatic variance component as a percentage of the total genetic variance. Enter Total genetic variance and Epistatic variance using the definitions and units below so the result can be reproduced.

Total genetic variance
A finite measured or assumed value greater than or equal to 0.
Epistatic variance
A finite measured or assumed value greater than or equal to 0.

How Epistasis Variance Share calculates the result

The published tool contract uses this rule: Express the epistatic variance component as a percentage of the total genetic variance.1

Epistasis share
The calculated epistasis share in %.

Limitations of Epistasis Variance Share

A ratio or percentage can conceal the scale of its numerator and denominator and becomes sensitive to measurement error when the denominator is small.

Alternative or Complementary measurements

Retain the original Total genetic variance and Epistatic variance values and their units alongside the result. Dominance Variance Share is useful when you instead need to express the dominance variance component as a percentage of the total genetic variance. Additive Variance Component provides another view by helping you derive the additive genetic variance by subtracting dominance and epistatic components from the total genetic variance.

References

  1. Genetic variance — Wikipedia contributors

Similar or alternative tools

  • Dominance Variance Share

    Express the dominance variance component as a percentage of the total genetic variance.

  • Additive Variance Component

    Derive the additive genetic variance by subtracting dominance and epistatic components from the total genetic variance.

  • Drift Variance

    Compute the expected one-generation variance in allele frequency under diploid Wright-Fisher drift: p × (1 - p) / (2Ne), where Ne is the effective number of breeding individuals.

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