Unmyelinated Conduction Velocity
Estimate unmyelinated axon conduction velocity as 0.5 times the square root of fibre diameter in micrometres. The coefficient is empirical and varies with membrane properties and temperature.
Description
Estimate unmyelinated axon conduction velocity as 0.5 times the square root of fibre diameter in micrometres. The coefficient is empirical and varies with membrane properties and temperature.
Unmyelinated Conduction Velocity applies one documented biological calculation to the values you provide. Estimate unmyelinated axon conduction velocity as 0.5 times the square root of fibre diameter in micrometres. The coefficient is empirical and varies with membrane properties and temperature.1
When to use Unmyelinated Conduction Velocity
Use this relationship for a rough physiological estimate when fibre diameter is known and the myelination model stated by the tool applies.
- Fibre diameter
- Unmyelinated fibre diameter in micrometres; must be greater than zero.
How Unmyelinated Conduction Velocity calculates the result
The implementation follows this calculation rule: Estimate unmyelinated axon conduction velocity as 0.5 times the square root of fibre diameter in micrometres. The coefficient is empirical and varies with membrane properties and temperature.
- Conduction velocity
- Action potential conduction velocity in metres per second.
Limitations of Unmyelinated Conduction Velocity
The diameter relationship is empirical and does not model temperature, internode length, membrane properties, species, fibre distribution, or disease. It must not be interpreted as a patient nerve-conduction study. The output is explicitly an estimate or proxy; preserve that label when reporting it.
Alternative or Complementary measurements
Measured latency over a known distance is preferable for experimental or clinical work. Record temperature, nerve segment, stimulus and recording sites, and whether the estimate refers to a single axon or a compound response.
References
-
Nerve conduction velocity — Wikipedia contributors
Similar or alternative tools
- Conduction Velocity
Estimate myelinated axon conduction velocity with the documented linear factor of about 6 metres per second per micrometre of fibre diameter.
- Membrane Time Constant
Compute the passive membrane time constant tau = R x C, converting megaohm-microfarads (seconds) to milliseconds.
- Nernst Membrane Potential
Compute the Nernst equilibrium potential at 37 degrees Celsius in millivolts: EMV = (61.5 / z) x log10(outsideConcentration / insideConcentration), signed positive for outward cation gradient driving force.