Conduction Velocity

Estimate myelinated axon conduction velocity with the documented linear factor of about 6 metres per second per micrometre of fibre diameter.

Description

Estimate myelinated axon conduction velocity with the documented linear factor of about 6 metres per second per micrometre of fibre diameter.

Conduction Velocity applies one documented biological calculation to the values you provide. Estimate myelinated axon conduction velocity with the documented linear factor of about 6 metres per second per micrometre of fibre diameter.1

When to use Conduction Velocity

Use this relationship for a rough physiological estimate when fibre diameter is known and the myelination model stated by the tool applies.

Fibre diameter
Myelinated fibre diameter in micrometres; must be greater than zero.

How Conduction Velocity calculates the result

The implementation follows this calculation rule: Estimate myelinated axon conduction velocity with the documented linear factor of about 6 metres per second per micrometre of fibre diameter.1

Conduction velocity
Action potential conduction velocity in metres per second.

Limitations of Conduction Velocity

The diameter relationship is empirical and does not model temperature, internode length, membrane properties, species, fibre distribution, or disease. It must not be interpreted as a patient nerve-conduction study. The output is explicitly an estimate or proxy; preserve that label when reporting it.

Alternative or Complementary measurements

Measured latency over a known distance is preferable for experimental or clinical work. Record temperature, nerve segment, stimulus and recording sites, and whether the estimate refers to a single axon or a compound response.

References

  1. Nerve conduction velocity — Wikipedia contributors

Similar or alternative tools

  • Unmyelinated Conduction Velocity

    Estimate unmyelinated axon conduction velocity as 0.5 times the square root of fibre diameter in micrometres. The coefficient is empirical and varies with membrane properties and temperature.

  • Membrane Time Constant

    Compute the passive membrane time constant tau = R x C, converting megaohm-microfarads (seconds) to milliseconds.

  • Nernst Membrane Potential

    Compute the Nernst equilibrium potential at 37 degrees Celsius in millivolts: EMV = (61.5 / z) x log10(outsideConcentration / insideConcentration), signed positive for outward cation gradient driving force.

Don't forget to set a bookmark for tool.io!
Privacy | Imprint | Cookies