Use this population- or quantitative-genetics calculation when genotype counts, variance components, pedigree relationships, and ploidy follow the definitions assumed by the tool.

Relationship coefficient

A finite measured or assumed value from -1 through 1.

The implementation follows this calculation rule: Compute the coancestry or kinship phi of two individuals as half of their additive relationship coefficient.

Coancestry phi

The calculated coancestry phi.

Allele frequencies and genetic parameters describe the sampled population and model. Population structure, relatedness, selection, genotyping error, non-random mating, environmental covariance, and omitted variance components can bias interpretation. Preserve the input values and units so the result can be audited and recalculated.

Inspect genotype counts and Hardy–Weinberg diagnostics, or fit a pedigree/genomic mixed model when individual records are available. Confidence intervals and replication across populations are more informative than a point estimate alone.

• Additive Variance Component

  Derive the additive genetic variance by subtracting dominance and epistatic components from the total genetic variance.

• Allele Count Total

  Count total allele copies at a diploid locus as twice the number of individuals.

• FST Fixation Index

  Compute the fixation index fst = (ht - hs) / ht for two populations at a two-allele locus.