Description
Return monoprotic acid/base concentrations from supplied pH/pKa.
Biochemical amounts, ionization and free energies depend on units, standard states, activities and molecular composition. A supplied concentration ratio or independent-group formula is one local model relation rather than a complete equilibrium or verified molecular characterization.
Return monoprotic acid/base concentrations from supplied pH/pKa.
When to use this tool
Use Henderson Hasselbalch Species Ratio Term when checking the stated biochemical amount, charge, equilibrium or material-basis convention.
How to use the tool and how it works
- Enter ph, pka, totalConcentration. Use the units and conventions below.
- Run the tool. Correct any format, range, or cross-field input error before interpreting the output.
- Read baseAcidRatio, acidConcentration, baseConcentration. Use the output convention below.
Return monoprotic acid/base concentrations from supplied pH/pKa. Require totalConcentration >= 0; baseAcidRatio = 10^(pH-pKa), split total through the two reciprocal Henderson-Hasselbalch fractions.1
| Input field | Meaning and units | Accepted input |
|---|---|---|
| ph | Ph | Required. Finite number. |
| pka | Pka | Required. Finite number. |
| totalConcentration | Total Concentration | Required. Finite number; minimum 0. |
| Output field | Interpretation | Returned shape |
|---|---|---|
| baseAcidRatio | Base Acid Ratio | Required. Finite number. |
| acidConcentration | Acid Concentration | Required. Finite number. |
| baseConcentration | Base Concentration | Required. Finite number. |
{
"input": {
"ph": 7,
"pka": 6,
"totalConcentration": 11
},
"output": {
"baseAcidRatio": 10,
"acidConcentration": 1,
"baseConcentration": 10
}
}Limitations and assumptions
- This assumes compatible acid/base activity approximations and one pair; actual solution pH, ionic strength and buffer capacity are not solved.
- Inputs must satisfy both the field types and the cross-field conditions above. Invalid input causes an error; a successful false flag or documented placeholder is a different result.
- Numeric calculations use binary floating point unless exact decimal-integer arithmetic is explicitly stated. No hidden measurement tolerance or decimal rounding is added; nonfinite or out-of-contract results are rejected. Numeric signed-zero results are exported as zero.
Alternative or Complementary methods
Use compatible standard states, verified chemical identity and an appropriate complete activity/speciation or measurement model for physical interpretation.
References
Similar or alternative tools
- Buffer Total Species Count
Return total supplied conjugate-species amount and base share.
- Protein Net Charge One Group Term
Return one ionizable group's fractional occupancy and charge.