Indirect Standardized SMR

Apply indirect standardization: compute expected deaths from standard age-specific rates and study exposure, divide observed by expected deaths for the SMR, and multiply that ratio by the standard population's crude rate to obtain an indirectly standardized rate.

Description

Apply indirect standardization: compute expected deaths from standard age-specific rates and study exposure, divide observed by expected deaths for the SMR, and multiply that ratio by the standard population's crude rate to obtain an indirectly standardized rate.

Apply indirect standardization: compute expected deaths from standard age-specific rates and study exposure, divide observed by expected deaths for the SMR, and multiply that ratio by the standard population's crude rate to obtain an indirectly standardized rate.1

When to use Indirect Standardized SMR

Use standardization to compare populations with different age compositions after aligning age-specific rates and standard weights exactly.

Standard rates
Reference (standard) population age-specific rates in events per person-year.
Study population
Study population exposed by the same age groups.
Observed deaths
Total deaths observed in the study population over the period.
Standard crude rate
Crude event rate in the standard population, expressed in the same units as the age-specific rates.

How the method works

Expected
Expected deaths from applying standard rates to study exposure.
SMR
Standardized mortality ratio, observed divided by expected deaths.
Crude rate
Crude death rate of the study population per person-year.
Standardized rate
Indirectly standardized rate: the standard population's crude rate multiplied by the SMR.

Limitations and assumptions

The standardized result is a weighted summary, not an observed crude rate. It changes with the reference population, and incompatible age bands or rate denominators invalidate the comparison.

Alternative or Complementary measures

Report crude and age-specific rates alongside the standardized value, and repeat the calculation with another accepted standard population when comparisons could depend on the chosen weights.

References

  1. Age adjustment — Wikipedia contributors

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