Use Inbreeding Coefficient when you need to compute the inbreeding coefficient f = (he - ho) / he, which may be negative when heterozygote excess occurs. Enter Observed heterozygosity and Expected heterozygosity using the definitions and units below so the result can be reproduced.

Observed heterozygosity

A finite measured or assumed value from 0 through 1.

Expected heterozygosity

A finite measured or assumed value.

The published tool contract uses this rule: Compute the inbreeding coefficient f = (he - ho) / he, which may be negative when heterozygote excess occurs.^[1]

Inbreeding coefficient F

The calculated inbreeding coefficient f.

The calculation does not propagate measurement uncertainty, sampling error, or biological and chemical variability. Observed heterozygosity must remain between 0 and 1.

Retain the original Observed heterozygosity and Expected heterozygosity values and their units alongside the result. Pedigree F Accumulated is useful when you instead need to accumulate an inbreeding coefficient as the base coefficient plus the remaining relationship budget times one path contribution. LD Coefficient D provides another view by helping you compute linkage disequilibrium coefficient D = f(AB) - p(A) * p(B); the signed result may be negative.

• Pedigree F Accumulated

  Accumulate an inbreeding coefficient as the base coefficient plus the remaining relationship budget times one path contribution.

• LD Coefficient D

  Compute linkage disequilibrium coefficient D = f(AB) - p(A) * p(B); the signed result may be negative.

• Pedigree Inbreeding Loop

  Compute the path contribution to an offspring inbreeding coefficient for one common ancestor loop.