Gibbs-Donnan Ratio

Compute the Gibbs-Donnan ratio as the concentration of permeant ion inside a cell divided by its concentration outside.

Description

Compute the Gibbs-Donnan ratio as the concentration of permeant ion inside a cell divided by its concentration outside.

Gibbs-Donnan Ratio is a focused biology tool that compute the Gibbs-Donnan ratio as the concentration of permeant ion inside a cell divided by its concentration outside. It calculates locally from the values you enter and exposes the result without changing the source observations.1

When to use Gibbs-Donnan Ratio

Use Gibbs-Donnan Ratio when you need to compute the Gibbs-Donnan ratio as the concentration of permeant ion inside a cell divided by its concentration outside. Enter Inside concentration and Outside concentration using the definitions and units below so the result can be reproduced.

Inside concentration
A finite measured or assumed value, expressed in M.
Outside concentration
A finite measured or assumed value, expressed in M.

How Gibbs-Donnan Ratio calculates the result

The published tool contract uses this rule: Compute the Gibbs-Donnan ratio as the concentration of permeant ion inside a cell divided by its concentration outside.

Gibbs-Donnan ratio
The calculated gibbs-donnan ratio.

Limitations of Gibbs-Donnan Ratio

A ratio or percentage can conceal the scale of its numerator and denominator and becomes sensitive to measurement error when the denominator is small.

Alternative or Complementary measurements

Retain the original Inside concentration and Outside concentration values and their units alongside the result. Donnan Potential is useful when you instead need to compute the equilibrium potential at 25 °C from the inside-to-outside concentration ratio. The base-10 Nernst factor is 59.16 mV per tenfold concentration gradient and is divided by ion valence. APTT Ratio provides another view by helping you compute the activated partial thromboplastin time ratio as the patient APTT divided by the control APTT.

References

  1. Gibbs–Donnan effect — Wikipedia contributors

Similar or alternative tools

  • Donnan Potential

    Compute the equilibrium potential at 25 °C from the inside-to-outside concentration ratio. The base-10 Nernst factor is 59.16 mV per tenfold concentration gradient and is divided by ion valence.

  • APTT Ratio

    Compute the activated partial thromboplastin time ratio as the patient APTT divided by the control APTT.

  • a/A Ratio

    Compute the arterial-to-alveolar oxygen ratio as PaO2 divided by the alveolar oxygen tension from the simplified alveolar gas equation.

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