Fick Diffusion Rate

Compute the magnitude of steady-state diffusion with Fick's first law. Concentration in mg/mL is equivalent to mg/cm³, and membrane thickness is converted from micrometres to centimetres so the result is in mg/s.

Description

Compute the magnitude of steady-state diffusion with Fick's first law. Concentration in mg/mL is equivalent to mg/cm³, and membrane thickness is converted from micrometres to centimetres so the result is in mg/s.

Fick Diffusion Rate is a focused biology tool that compute the magnitude of steady-state diffusion with Fick's first law. Concentration in mg/mL is equivalent to mg/cm³, and membrane thickness is converted from micrometres to centimetres so the result is in mg/s. It calculates locally from the values you enter and exposes the result without changing the source observations.1

When to use Fick Diffusion Rate

Use Fick Diffusion Rate when you need to compute the magnitude of steady-state diffusion with Fick's first law. Concentration in mg/mL is equivalent to mg/cm³, and membrane thickness is converted from micrometres to centimetres so the result is in mg/s. Enter Diffusion coefficient, Area, Concentration difference, and Membrane thickness using the definitions and units below so the result can be reproduced.

Diffusion coefficient
Diffusion coefficient in square centimetres per second.
Area
Membrane surface area in square centimetres.
Concentration difference
Magnitude of the concentration difference across the membrane.
Membrane thickness
Membrane thickness in micrometres.

How Fick Diffusion Rate calculates the result

The published tool contract uses this rule: Compute the magnitude of steady-state diffusion with Fick's first law. Concentration in mg/mL is equivalent to mg/cm³, and membrane thickness is converted from micrometres to centimetres so the result is in mg/s.

Diffusion rate
Magnitude of the steady-state diffusion rate.

Limitations of Fick Diffusion Rate

A ratio or percentage can conceal the scale of its numerator and denominator and becomes sensitive to measurement error when the denominator is small.

Alternative or Complementary measurements

Retain the original Diffusion coefficient, Area, Concentration difference, and Membrane thickness values and their units alongside the result. BrdU Incorporation Rate is useful when you instead need to compute the percentage of BrdU positive cells relative to the total counted cell population. Specific Growth Rate provides another view by helping you calculate the specific growth rate in inverse hours from two counts.

References

  1. Fick's laws of diffusion — Wikipedia contributors

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